Evidence map›Paper›PMID 29619747›Full record

ArticleChinese journal of integrative medicine2019

Shexiang Tongxin Dropping Pill () Protects against Na

Shan Lin, Jiu-Mao Lin, Ling Zhang, Da-Xin Chen, Fei Xiao, Hong-Wei Chen, You-Qin Chen, Yu-Ling Zhu, Jian-Feng Chu, Jun Peng

Abstract read
PubMed Publisher
In one paragraph

Article in Chinese journal of integrative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Sodium dithionate (NaToxicology reports · 2022
    Article
  7. Sheng Mai San protects H9C2 cells against hyperglycemia-induced apoptosis.BMC complementary and alternative medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shan LinAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Jiu-Mao LinAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Ling ZhangAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Da-Xin ChenAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Fei XiaoAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Hong-Wei ChenAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
You-Qin ChenInner Mongolia Conba Pharmaceutical Co., Ltd., Shanghai, 201318, China.
Yu-Ling ZhuCHEN Ke-ji Academic Thought Heritage Studio, Fuzhou, 350122, China.
Jian-Feng ChuAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Jun PengAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. pjunlab@hotmail.com.
Fujian University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the protective effects of Shexiang Tongxin Dropping Pill (, STP) on Na

methodsThe cell viability and levels of mRNA and protein expression in H9c2 cells were determined following Na

resultsSTP pretreatment significantly increased the viability and inhibited aberrant morphological changes in H9c2 cardiomyoblast cells induced by Na

conclusionsSTP was strongly cardioprotective in hypoxia-reoxygenation injury by preventing hypoxic damage and inhibiting cellular apoptosis. These results further support the use of STP as an effective drug for the treatment of ischemic heart disease.

Indexed as

AnimalsApoptosisbcl-2-Associated X ProteinCell HypoxiaCell LineCell SurvivalDrugs, Chinese HerbalOxygenProtective AgentsProto-Oncogene Proteins c-bcl-2RatsSulfatesbcl-2-Associated X ProteinDrugs, Chinese HerbalOxygenProtective AgentsProto-Oncogene Proteins c-bcl-2shexiang tongxinsodium dithionateSulfatesapoptosisChinese medicinemyocardial ischemiaNa2S2O4-induced hypoxia-reoxygenation injuryShexiang Tongxin Dropping Pill

Identifiers

PMID29619747
OpenAlexW2795396202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.