ArticleEuropean journal of epidemiology2018
Performing studies using the UK Clinical Practice Research Datalink: to link or not to link?
Article in European journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- R WE ready for reimbursement? A round-up of developments in real-world evidence relating to health technology assessment: part 26.Journal of comparative effectiveness research · 2026Review
- Can the epidemiology of zoonotic disease be studied in routine health records? A feasibility study of the Clinical Practice Research Datalink (CPRD).One health (Amsterdam, Netherlands) · 2025Article
- Cohort studies on 71 outcomes among people with atopic eczema in UK primary care data.Nature communications · 2024Article
- R WE ready for reimbursement? A round up of developments in real-world evidence relating to health technology assessment: part 13.Journal of comparative effectiveness research · 2023Article
- Association between Inhaled βInternational journal of chronic obstructive pulmonary disease · 2022Article
- Non-benzodiazepine hypnotic use for sleep disturbance in people aged over 55 years living with dementia: a series of cohort studies.Health technology assessment (Winchester, England) · 2021Article
- Objectives, design and main findings until 2020 from the Rotterdam Study.European journal of epidemiology · 2020Article
- Questionable Survival Benefit of Aspirin Use in Patients With Biliary Tract Cancer-Reply.JAMA oncology · 2020Article
- Prevalence of comorbid mental and physical illnesses and risks for self-harm and premature death among primary care patients diagnosed with fatigue syndromes.Psychological medicine · 2020Article
- Gender Differences in Inhaled Pharmacotherapy Utilization in Patients with Obstructive Airway Diseases (OADs): A Population-Based Study.International journal of chronic obstructive pulmonary disease · 2020Article
- Performance and clinical utility of supervised machine-learning approaches in detecting familial hypercholesterolaemia in primary care.NPJ digital medicine · 2020Article
- Effectiveness of two-drug therapy versus monotherapy as initial regimen in hypertension: A propensity score-matched cohort study in the UK Clinical Practice Research Datalink.Pharmacoepidemiology and drug safety · 2019Observational
- Linkage of the UK Clinical Practice Research Datalink with the national cancer registry.European journal of epidemiology · 2019Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Clinical Practice Research Datalink (CPRD) is a repository of electronic medical records collected during routine primary care clinical practice in the UK, and is one of the most widely used sources of real-world data for healthcare research. Although CPRD provides access to comprehensive longitudinal patient records, the data does not fully capture diagnoses or outcomes occurring in secondary care and/or mortality. We provide here an overview of CPRD and the potential bias when using unlinked data in certain situations. Linkage of CPRD to other datasets can help to overcome these limitations. We discuss when to consider linkage to secondary care, disease-specific data sources or the official mortality data when conducting research using CPRD data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.