Evidence map›Paper›PMID 29619642›Full record

ArticleFunctional & integrative genomics2018

Genome sequence and comparative analysis of Bacillus cereus BC04, reveals genetic diversity and alterations for antimicrobial resistance.

Vijaya Bharathi Srinivasan, Mahavinod Angrasan, Neha Chandel, Govindan Rajamohan

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In one paragraph

Article in Functional & integrative genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vijaya Bharathi SrinivasanBacterial Signaling and Drug Resistance Laboratory, CSIR-Institute of Microbial Technology, Sector 39-A, Chandigarh, 160036, India.
Mahavinod AngrasanBacterial Signaling and Drug Resistance Laboratory, CSIR-Institute of Microbial Technology, Sector 39-A, Chandigarh, 160036, India.
Neha ChandelBacterial Signaling and Drug Resistance Laboratory, CSIR-Institute of Microbial Technology, Sector 39-A, Chandigarh, 160036, India.
Govindan RajamohanBacterial Signaling and Drug Resistance Laboratory, CSIR-Institute of Microbial Technology, Sector 39-A, Chandigarh, 160036, India. rmohan@imtech.res.in.
Institute of Microbial Technology · IN

Funding

Council of Scientific and Industrial Research BSC0119HDepartment of Biotechnology , Ministry of Science and Technology BT/01/IYBA/2009Department of Biotechnology , Ministry of Science and Technology BT/HRD/NBA/34/01/2012Science and Engineering Research Board SB/YS/LS-177/2014
6 · The paper itself

Abstract

In this study, we delineated the genome sequence of a Bacillus cereus strain BC04 isolated from a stool sample in India. The draft genome is 5.1 Mb in size and consists of total 109 scaffolds, GC content is 35.2% with 5182 coding genes. The comparative analysis with other completely sequenced genomes highlights the unique presence of genomic islands, hemolysin, capsular synthetic protein, modifying enzymes accC7 and catA15, regulators of antibiotic resistance MarR and LysR with annotated functions related to virulence, stress response, and antimicrobial resistance. Overall, this study not only signifies the genetic diversity in gut isolate BC04 in particular, but also pinpoints the presence of unique genes possessed by B. cereus which can be pertinently exploited to design novel drugs and intervention strategies for the treatment of food borne diseases.

Indexed as

Genome, BacterialPolymorphism, GeneticBacillus cereusDrug Resistance, BacterialMolecular Sequence AnnotationPhylogenyActive effluxAntimicrobial resistanceBacillusHuman microbiomeIndian gut isolate

Identifiers

PMID29619642
OpenAlexW2795588771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.