ReviewCurrent pain and headache reports2018
America's Opioid Epidemic: a Comprehensive Review and Look into the Rising Crisis.
Review in Current pain and headache reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04680741 (Application Based Addiction Treatment Adherence Trial), which is not on this map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application Based Addiction Treatment Adherence Trial: a Pilot Study
Who cites it
35 citing papers in PubMed, 78 citations in OpenAlex.
- Longitudinal polysubstance use patterns and non-fatal overdose: A repeated measures latent class analysis.The International journal on drug policy · 2025Article
- Neuropsychological mechanisms of observational learning in human placebo effects.Psychopharmacology · 2025Review
- Pharmaceutical industry use of key opinion leaders to market prescription opioids: A review of internal industry documents.Exploratory research in clinical and social pharmacy · 2024Review
- Misuse, Abuse and Medication Errors' Adverse Events Associated with Opioids-A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Child Protection System Interactions for Children With Positive Urine Screens for Illicit Drugs.JAMA network open · 2024Article
- Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels.Frontiers in molecular neuroscience · 2024Article
- rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels.Frontiers in molecular neuroscience · 2024Article
- Self-reported Impacts of the COVID-19 Pandemic and Economic Inflation on the Well-being of Low-income U.S. Veterans.Journal of community health · 2023Article
- Paternal morphine exposure in rats reduces social play in adolescent male progeny without affecting drug-taking behavior in juvenile males or female offspring.Molecular and cellular neurosciences · 2023Article
- Can Anti-inflammatory Drugs used in Plastic Surgery Procedures Increase the Risk of Hematoma?Aesthetic plastic surgery · 2023Review
- HIV-1 and opiates modulate miRNA profiles in extracellular vesicles.Frontiers in immunology · 2023Article
- Opioid use after outpatient elective general surgery: quantifying the burden of persistent use.British journal of pain · 2022Article
- Factors associated with non-medical use of prescription drugs among individuals with a legitimate prescription for medical purposes: A population-based study.Nordisk alkohol- & narkotikatidskrift : NAT · 2022Article
- Exploiting Injury-Induced Peripheral Opioid Receptor Changes in Novel Analgesic Development for Chronic Pain.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Quality of Life and Opioid Use Motives: Direct and Indirect Associations with Risky Opioid Use in a Community Sample of Adults.Substance use & misuse · 2022Article
- Sex differences in type and occurrence of adverse reactions to opioid analgesics: a retrospective cohort study.BMJ open · 2021Article
- Fentanyl-related overdose during incarceration: a comprehensive review.Health & justice · 2021Article
- Sex-dependent effects of an Hnrnph1 mutation on fentanyl addiction-relevant behaviors but not antinociception in mice.Genes, brain, and behavior · 2021Article
- Generational Effects of Opioid Exposure.Encyclopedia · 2021Article
- Point-of-care naloxone distribution in the emergency department: A pilot study.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewIn the USA, there has been a sharp increase in heroin, prescription opiate, and illicitly manufactured fentanyl abuse with overdoses tripling since the 1990s. Several states have been deemed as "high-burden" abuse states where there is a greater proportion of synthetic opiate use. During the same period that prescription limitations were initially implemented throughout the country, the fentanyl epidemic started nationwide. RECENT
findingsIn the setting of data demonstrating an almost fourfold increase in overdose deaths from 1999 to 2008, states began restricting access to Food and Drug Agency (FDA) approved opioid medications. Another factor further exacerbating the opioid crises is that the cost of all formulations of naloxone has increased significantly over the past several years. In order to combat the opioid epidemic, stricter prescribing practices and prescription-monitoring programs have been instituted. Also, improvements in abuse-deterrent strategies for all opioid preparations can play an important role by increasing the safety of these medications and is a major focus of the FDA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.