Evidence map›Paper›PMID 29619424›Full record

ArticleHepatology communications2018

Liver stiffness measurement predicted liver-related events and all-cause mortality: A systematic review and nonlinear dose-response meta-analysis.

Junna Wang, Jiajun Li, Quan Zhou, Dandan Zhang, Qiu Bi, Yulin Wu, Wenxiang Huang

RetractedAbstract readRetracted Publication
In one paragraph

Article in Hepatology communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Article
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  6. Review
  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Junna WangDepartment of Infectious Diseases First Affiliated Hospital of Chongqing Medical University Chongqing China.
Jiajun LiDepartment of Infectious Diseases First Affiliated Hospital of Chongqing Medical University Chongqing China.
Quan ZhouDepartment of Science and Education First People's Hospital of Changde City Hunan China.
Dandan ZhangDepartment of Gerontology Second Affiliated Hospital of Chongqing Medical University Chongqing China.
Qiu BiDepartment of Radiology First Affiliated Hospital of Chongqing Medical University Chongqing China.
Yulin WuDepartment of Hepatobiliary Surgery Second Affiliated Hospital of Chongqing Medical University Chongqing China.
Wenxiang HuangDepartment of Infectious Diseases First Affiliated Hospital of Chongqing Medical University Chongqing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have investigated the prognosis value of the liver stiffness measurement (LSM) by transient elastography in assessing the risk of liver-related events (LREs) and all-cause mortality in patients with chronic liver disease (CLD). However, the shape of the dose-response relationship between them remains unclear. We searched PubMed, Embase, the Cochrane Library, and reference lists of articles for studies published up to July 1, 2017, that assessed the LSM in predicting LREs and all-cause mortality among subjects with CLD. Fifty-four observational cohort studies with 35,249 participants were included. Summary relative risks (RRs) were calculated using a random-effects model, and a restricted cubic spline function was used to model the dose-response association. LREs and all-cause mortality were increased in subjects with a high LSM (LRE: RR, 7.90; 95% confidence interval [CI], 5.65, 11.05;

Identifiers

PMID29619424
PMCPMC5880200

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.