Evidence map›Paper›PMID 29619418›Full record

ArticleHepatology communications2018

The Role of Intestinal C-type Regenerating Islet Derived-3 Lectins for Nonalcoholic Steatohepatitis.

Sena Bluemel, Lirui Wang, Cameron Martino, Suhan Lee, Yanhan Wang, Brandon Williams, Angela Horvath, Vanessa Stadlbauer, Karsten Zengler, Bernd Schnabl

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Sena BluemelDepartment of Medicine University of California San Diego La Jolla CA.ORCID 0000-0002-0518-5505
Lirui WangDepartment of Medicine University of California San Diego La Jolla CA.
Cameron MartinoDepartment of Pediatrics Division of Host-Microbe Systems and Therapeutics San Diego CA.
Suhan LeeDepartment of Medicine University of California San Diego La Jolla CA.
Yanhan WangDepartment of Medicine University of California San Diego La Jolla CA.
Brandon WilliamsDepartment of Medicine University of California San Diego La Jolla CA.
Angela HorvathDepartment of Internal Medicine, Division of Gastroenterology and Hepatology Medical University of Graz Graz Austria.
Vanessa StadlbauerDepartment of Internal Medicine, Division of Gastroenterology and Hepatology Medical University of Graz Graz Austria.
Karsten ZenglerDepartment of Pediatrics Division of Host-Microbe Systems and Therapeutics San Diego CA.
Bernd SchnablDepartment of Medicine University of California San Diego La Jolla CA.
University of California San Diego · USMedical University of Graz · AT

Funding

Microbiome and intestinal innate immune response in alcoholic liver diseaseR01AA020703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHNABL, BERND G. · 2011 to 2020
$3.6M
Microbiome as Therapeutic Target in Alcoholic HepatitisU01AA021856 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRENNER, DAVID A., SCHNABL, BERND G. · 2013 to 2017
$2.1M
The Role of the Intestinal Mycobiome in Alcoholic Liver DiseaseU01AA024726 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHNABL, BERND G. · 2017 to 2017
$353k
BLRD VA I01 BX002213NIAAA NIH HHS R01 AA020703NIAAA NIH HHS U01 AA021856NIAAA NIH HHS U01 AA024726
6 · The paper itself

Abstract

C-type regenerating islet derived-3 (Reg3) lectins defend against pathogens and keep commensal bacteria at a distance. Deficiency of

Identifiers

PMID29619418
PMCPMC5880191
OpenAlexW2794334679

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.