Evidence map›Paper›PMID 29619269›Full record

ArticleBone research2018

Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.

Shan-Shan Rao, Yin Hu, Ping-Li Xie, Jia Cao, Zhen-Xing Wang, Jiang-Hua Liu, Hao Yin, Jie Huang, Yi-Juan Tan, Juan Luo and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 1 synthesis or guideline pooled it, 168 citations in OpenAlex.

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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Shan-Shan Rao *1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Yin Hu *1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Ping-Li Xie4Department of Forensic Science, School of Basic Medical Sciences, Central South University, Changsha, Hunan 410013 China.
Jia Cao1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Zhen-Xing Wang1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Jiang-Hua Liu1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Hao Yin1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Jie Huang1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Yi-Juan Tan1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Juan Luo1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Ming-Jie Luo5Xiangya Nursing School, Central South University, Changsha, Hunan 410013 China.
Si-Yuan Tang5Xiangya Nursing School, Central South University, Changsha, Hunan 410013 China.
Tuan-Hui Chen1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Ling-Qing Yuan6Second Xiangya Hospital, Central South University, Changsha, Hunan 410011 China.
Er-Yuan Liao6Second Xiangya Hospital, Central South University, Changsha, Hunan 410011 China.
Ran Xu6Second Xiangya Hospital, Central South University, Changsha, Hunan 410011 China.
Zheng-Zhao Liu1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Chun-Yuan Chen1Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Hui Xie3Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan 410008 China.
Central South University · CNXiangya Hospital Central South University · CNSecond Xiangya Hospital of Central South University · CNSoil and Fertilizer Institute of Hunan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a frequent complication of chronic inflammatory diseases and increases in the pro-inflammatory cytokines make an important contribution to bone loss by promoting bone resorption and impairing bone formation. Omentin-1 is a newly identified adipocytokine that has anti-inflammatory effects, but little is known about the role of omentin-1 in inflammatory osteoporosis. Here we generated global

Identifiers

PMID29619269
PMCPMC5876344
OpenAlexW2794836426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.