ArticleChemical science2018
Unequivocal determination of caulamidines A and B: application and validation of new tools in the structure elucidation tool box.
Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed, 69 citations in OpenAlex.
- Structural determination of natural products at speeds and scale of high-throughput screening.Natural product reports · 2026Review
- Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules.Magnetic resonance in chemistry : MRC · 2026Review
- Artificial intelligence for natural product drug discovery.Nature reviews. Drug discovery · 2023Review
- Rare Caulamidine Hexacyclic Alkaloids from the Marine AscidianJournal of natural products · 2023Article
- Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023Review
- Programmable alignment media from self-assembled oligopeptide amphiphiles for the measurement of independent sets of residual dipolar couplings in organic solvents.Chemical science · 2022Article
- NMR-Based Configurational Assignments of Natural Products: Gibbs Sampling and Bayesian Inference Using Floating Chirality Distance Geometry Calculations.Marine drugs · 2021Article
- Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria.Natural product reports · 2021Review
- Article
- NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp.Magnetic resonance in chemistry : MRC · 2021Article
- Deciphering the chemical instability of sphaeropsidin A under physiological conditions - degradation studies and structural elucidation of the major metabolite.Organic & biomolecular chemistry · 2020Article
- Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements.Chemical science · 2020Article
- Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A.Chemical communications (Cambridge, England) · 2020Article
- The Phylum Bryozoa: From Biology to Biomedical Potential.Marine drugs · 2020Review
- Determination of Complex Small-Molecule Structures Using Molecular Alignment Simulation.Angewandte Chemie (International ed. in English) · 2020Article
- Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS).Journal of natural products · 2019Article
- Characterization by Empirical and Computational Methods of Dictyospiromide, an Intriguing Antioxidant Alkaloid from the Marine AlgaOrganic letters · 2019Article
- Natural Products as a Foundation for Drug Discovery.Current protocols in pharmacology · 2019Review
- The Phylum Bryozoa as a Promising Source of Anticancer Drugs.Marine drugs · 2019Review
- Elucidation of Spirodactylone, a Polycyclic Alkaloid from the Sponge Dactylia sp., and Nonenzymatic Generation from the Co-metabolite Denigrin B.Organic letters · 2019Article
Corrections and comments
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Authors and funding
18 authors at 7 institutions in 5 countries.
Funding
Abstract
Ambiguities and errors in the structural assignment of organic molecules hinder both drug discovery and total synthesis efforts. Newly described NMR experimental approaches can provide valuable structural details and a complementary means of structure verification. The caulamidines are trihalogenated alkaloids from a marine bryozoan with an unprecedented structural scaffold. Their unique carbon and nitrogen framework was deduced by conventional NMR methods supplemented by new experiments that define 2-bond heteronuclear connectivities, reveal very long-range connectivity data, or visualize the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.