Evidence map›Paper›PMID 29619196›Full record

ArticleChemical science2017

Dual targeting of the cancer antioxidant network with 1,4-naphthoquinone fused Gold(i) N-heterocyclic carbene complexes.

R McCall, M Miles, P Lascuna, B Burney, Z Patel, K J Sidoran, V Sittaramane, J Kocerha, D A Grossie, J L Sessler and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Unravelling the novel insights between miR-7 and Parkinson's disease (PD).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Di-IUCrData · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

R McCallDepartment of Chemistry , Georgia Southern University , Statesboro , GA 30460 , USA . Email: jfarambula@cm.utexas.edu.
M MilesDepartment of Chemistry , Wright State University , 3640 Colonel Glenn Hwy , Dayton , Ohio 45435 , USA . Email: kuppuswamy.arumugam@wright.edu.
P LascunaDepartment of Biology , Georgia Southern University , Statesboro , GA 30460 , USA.
B BurneyDepartment of Chemistry , Georgia Southern University , Statesboro , GA 30460 , USA . Email: jfarambula@cm.utexas.edu.
Z PatelDepartment of Chemistry , Georgia Southern University , Statesboro , GA 30460 , USA . Email: jfarambula@cm.utexas.edu.
K J SidoranDepartment of Chemistry , St. Bonaventure University , St. Bonaventure , NY 14778 , USA.ORCID 0000-0002-5315-2046
V SittaramaneDepartment of Biology , Georgia Southern University , Statesboro , GA 30460 , USA.
J KocerhaDepartment of Chemistry , Georgia Southern University , Statesboro , GA 30460 , USA . Email: jfarambula@cm.utexas.edu.
D A GrossieDepartment of Chemistry , Wright State University , 3640 Colonel Glenn Hwy , Dayton , Ohio 45435 , USA . Email: kuppuswamy.arumugam@wright.edu.
J L SesslerDepartment of Chemistry , University of Texas , 105 E. 24th St. , Austin , TX 78712-1224 , USA.ORCID 0000-0002-9576-1325
K ArumugamDepartment of Chemistry , Wright State University , 3640 Colonel Glenn Hwy , Dayton , Ohio 45435 , USA . Email: kuppuswamy.arumugam@wright.edu.
J F ArambulaDepartment of Chemistry , Georgia Southern University , Statesboro , GA 30460 , USA . Email: jfarambula@cm.utexas.edu.ORCID 0000-0003-2342-8440
Edinboro University · USWright State University · USSt. Bonaventure University · USThe University of Texas at Austin · US

Funding

Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
NCI NIH HHS R01 CA068682
6 · The paper itself

Abstract

To achieve a systems-based approach to targeting the antioxidant pathway, 1,4-naphthoquinone annulated N-heterocyclic carbene (NHC) [bis(1,3-dimesityl-4,5-naphthoquino-imidazol-2-ylidene)-gold(i)] [silver(i) dichloride] (

Identifiers

PMID29619196
PMCPMC5859730
OpenAlexW2737884943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.