Evidence map›Paper›PMID 29619081›Full record

ArticleBiotechnology for biofuels2018

Lignin from hydrothermally pretreated grass biomass retards enzymatic cellulose degradation by acting as a physical barrier rather than by inducing nonproductive adsorption of enzymes.

Demi T Djajadi, Mads M Jensen, Marlene Oliveira, Anders Jensen, Lisbeth G Thygesen, Manuel Pinelo, Marianne Glasius, Henning Jørgensen, Anne S Meyer

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. PreliminaryVeterinary world · 2026
    Article
  3. Article
  4. Article
  5. Review
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  7. Article
  8. Review
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  10. Article
  11. Cellulases adsorb reversibly on biomass lignin.Biotechnology and bioengineering · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Demi T Djajadi1Department of Chemical and Biochemical Engineering, Technical University of Denmark, Søltofts Plads Building 229, 2800 Kongens Lyngby, Denmark.
Mads M Jensen2Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
Marlene Oliveira1Department of Chemical and Biochemical Engineering, Technical University of Denmark, Søltofts Plads Building 229, 2800 Kongens Lyngby, Denmark.
Anders Jensen3Department of Geosciences and Natural Resource Management, University of Copenhagen, Rolighedsvej 23, 1958 Frederiksberg C, Denmark.
Lisbeth G Thygesen3Department of Geosciences and Natural Resource Management, University of Copenhagen, Rolighedsvej 23, 1958 Frederiksberg C, Denmark.
Manuel Pinelo1Department of Chemical and Biochemical Engineering, Technical University of Denmark, Søltofts Plads Building 229, 2800 Kongens Lyngby, Denmark.
Marianne Glasius2Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
Henning Jørgensen1Department of Chemical and Biochemical Engineering, Technical University of Denmark, Søltofts Plads Building 229, 2800 Kongens Lyngby, Denmark.
Anne S Meyer1Department of Chemical and Biochemical Engineering, Technical University of Denmark, Søltofts Plads Building 229, 2800 Kongens Lyngby, Denmark.ORCID 0000-0001-8910-9931
Technical University of Denmark · DKUniversity of Copenhagen · DKAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLignin is known to hinder efficient enzymatic conversion of lignocellulose in biorefining processes. In particular, nonproductive adsorption of cellulases onto lignin is considered a key mechanism to explain how lignin retards enzymatic cellulose conversion in extended reactions.

resultsLignin-rich residues (LRRs) were prepared via extensive enzymatic cellulose degradation of corn stover (

conclusionsThe study suggests that lignin from hydrothermally pretreated grass biomass retards enzymatic cellulose degradation by acting as a physical barrier blocking the access of enzymes to cellulose rather than by inducing retardation through nonproductive adsorption of enzymes.

Indexed as

AdsorptionApparent surface abundanceCellulasesDepolymerizationEnzymatic hydrolysisInhibitionLigninPhysical barrierS/G ratioβ-O-4 linkage

Identifiers

PMID29619081
PMCPMC5880018
OpenAlexW2797437587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.