Evidence map›Paper›PMID 29619025›Full record

ReviewFrontiers in immunology2018

Mast Cells and Innate Lymphoid Cells: Underappreciated Players in CNS Autoimmune Demyelinating Disease.

Melissa A Brown, Rebecca B Weinberg

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Impact of TNF and IL-33 Cytokines on Mast Cells in Neuroinflammation.International journal of molecular sciences · 2024
    Review
  6. Tumor-infiltrating mast cells stimulate ICOSJournal of advanced research · 2024
    Article
  7. Expression levels ofHeliyon · 2024
    Article
  8. Article
  9. Mast Cells and Interleukins.International journal of molecular sciences · 2022
    Review
  10. Review
  11. Review
  12. Circulating CCR6Clinical & translational immunology · 2022
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Mast cells and angiogenesis in multiple sclerosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020
    Review
  20. [Headache in multiple sclerosis].Der Nervenarzt · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Melissa A BrownDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Rebecca B WeinbergDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Northwestern University · US

Funding

Mechanisms of mast cell influence on EAE disease courseR01NS047578 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BROWN, MELISSA A · 2006 to 2010
$1.6M
Mechanisms Regulating Reduced c-Kit-Dependent EAE Susceptibility in Male SJL MiceR21NS081598 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BROWN, MELISSA A · 2012 to 2013
$418k
NINDS NIH HHS R01 NS047578NINDS NIH HHS R21 NS081598
6 · The paper itself

Abstract

Multiple sclerosis (MS) and its mouse model, experimental autoimmune encephalomyelitis, are autoimmune CNS inflammatory diseases. As a result of a breakdown in the relatively impermeable blood-brain barrier (BBB) in affected individuals, myelin-specific CD4

Indexed as

AnimalsDemyelinating Autoimmune Diseases, CNSHumansImmunity, InnateInterleukin-33LymphocytesMast CellsMeningesInterleukin-33experimental autoimmune encephalomyelitisinnate immunityinnate lymphoid cellsmast cellsmeningesmultiple sclerosissex-dimorphic autoimmunitytestosterone

Identifiers

PMID29619025
PMCPMC5871669
OpenAlexW2793690994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.