Evidence map›Paper›PMID 29619016›Full record

ArticleFrontiers in microbiology2018

Cyclic AMP Pathway Activation and Extracellular Zinc Induce Rapid Intracellular Zinc Mobilization in

Lasse Kjellerup, Anne-Marie L Winther, Duncan Wilson, Anja T Fuglsang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Protein kinase A signaling regulates immune evasion by shaving and concealing fungal β-1,3-glucan.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Article
  4. Zinc homeostasis in the secretory pathway in yeast.Current opinion in chemical biology · 2020
    Review
  5. Transcription factors and transporters in zinc homeostasis: lessons learned from fungi.Critical reviews in biochemistry and molecular biology · 2020
    Review
  6. The intersection of host and fungus through the zinc lens.Current opinion in microbiology · 2019
    Review
  7. Frontiers in microbiology · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Lasse KjellerupDepartment of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg, Denmark.
Anne-Marie L WintherPcovery ApS, Copenhagen, Denmark.
Duncan WilsonMedical Research Council Centre for Medical Mycology, University of Aberdeen, Aberdeen Fungal Group, Aberdeen, United Kingdom.
Anja T FuglsangDepartment of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg, Denmark.
University of Copenhagen · DKUniversity of Aberdeen · GB

Funding

Medical Research Council MR/N006364/1Wellcome Trust
6 · The paper itself

Abstract

Zinc is an essential micronutrient, required for a range of zinc-dependent enzymes and transcription factors. In mammalian cells, zinc serves as a second messenger molecule. However, a role for zinc in signaling has not yet been established in the fungal kingdom. Here, we used the intracellular zinc reporter, zinbo-5, which allowed visualization of zinc in the endoplasmic reticulum and other components of the internal membrane system in

Indexed as

cAMPCandida albicansERsignalingzinc

Identifiers

PMID29619016
PMCPMC5871664
OpenAlexW2789361973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.