Evidence map›Paper›PMID 29618927›Full record

ArticleNeuropsychiatric disease and treatment2018

Serum levels of GPER-1 in euthymic bipolar patients.

Fatma Özlem Orhan, Ergül Belge Kurutaş, Adem Doğaner, Ebru Türker, Safiye Şeyma Taner Özcü, Meltem Güngör, Seyfettin Çakmak

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  7. G protein coupled oestrogen receptor 1, aromatase, 17β-HSD and cAMP level in mutational falsetto.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fatma Özlem OrhanDepartment of Psychiatry, Faculty of Medicine, Kahramanmaraş Sütçüimam University, Kahramanmaras, Turkey.
Ergül Belge KurutaşDepartment of Biochemistry, Faculty of Medicine, Kahramanmaraş Sütçüimam University, Kahramanmaras, Turkey.
Adem DoğanerDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Kahramanmaraş Sütçüimam University, Kahramanmaras, Turkey.
Ebru TürkerDepartment of Psychiatry, Faculty of Medicine, Kahramanmaraş Sütçüimam University, Kahramanmaras, Turkey.
Safiye Şeyma Taner ÖzcüDepartment of Bioengineering, Institute of Science, Kahramanmaraş Sütçüimam University, Kahramanmaras, Turkey.
Meltem GüngörVocational High School, Toros University, Mersin, Turkey.
Seyfettin ÇakmakDepartment of Psychiatry, Faculty of Medicine, Kahramanmaraş Sütçüimam University, Kahramanmaras, Turkey.
Kahramanmaraş Sütçü İmam University · TRToros University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEstrogen and its receptors have been suggested as playing a role in the pathogenesis of bipolar disorder (BD). Estrogen functions through the estrogen receptors alpha and beta and the recently discovered G-protein-coupled estrogen receptor-1 (GPER-1). The aim of this study was to evaluate serum GPER-1 levels in euthymic BD patients. PATIENTS AND

methodsThe study population consisted of 38 euthymic outpatients meeting the criteria for BD in the

resultsSerum GPER-1 levels were measured in both patients and controls and found to be significantly higher in the BD patients than in controls. These results were not influenced by the medications in use.

conclusionThe results of this study demonstrated that GPER-1 may play a role in BD pathophysiology.

Indexed as

bipolarestrogen receptoreuthymicGPER-1sex hormones

Identifiers

PMID29618927
PMCPMC5875407
OpenAlexW2790478332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.