ArticleNature2018
The evolutionary history of vertebrate RNA viruses.
Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 494 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
494 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of epidemiological modelling in response to lumpy skin disease outbreaks.Frontiers in veterinary science · 2024Pooled it
- The origins and evolution of the RNA virome in land flora.Molecular plant · 2026Article
- Exploring the ecological drivers of bacteriophage diversity and functional viral potential in the skin of the axolotl Ambystoma altamirani.FEMS microbiology ecology · 2026Article
- Viromic Koch's postulates resolve iron prawn syndrome etiology.Journal of virology · 2026Article
- RNAViruses · 2026Review
- Direct visualization of RNA virus and evaluation of drug effect in living cells by catalytically transformable DNA cube.Science advances · 2026Article
- Nucleocapsid-like cryo-EM structure of influenza B virus.PLoS pathogens · 2026Article
- Empowering One Health with metagenomics.One health outlook · 2026Review
- Identification of novel hepaciviruses in rock pigeon (Columba livia [Gmelin, 1789]), rusty-margined flycatcher (Myiozetetes cayanensis [Linnaeus, 1766]), and Hispaniolan amazon (Amazona ventralis [Statius Muller, 1776]).Archives of virology · 2026Article
- Metagenomic Characterization and Molecular Screening of Pathogens in Freshwater Amphipods (Pathogens (Basel, Switzerland) · 2026Article
- Metatranscriptomic discovery of a novel viral class from the Yangshan deep-water port virosphere.Archives of virology · 2026Article
- Evidence of Juquitiba and Jaborá Orthohantavirus Co-Circulation in Rodent Communities of Argentina.EcoHealth · 2026Article
- Near-complete genome sequences of marna- and nora-like picornaviruses from small pond water in Japan.Microbiology resource announcements · 2026Article
- Further characterization of infection mechanisms and transmission dynamics of rustrela virus in rodentThe Journal of general virology · 2026Article
- Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis).Journal of fish diseases · 2026Article
- Elucidating the enigmatic biology of arteriviruses through receptor discovery.Journal of virology · 2026Review
- A molecular survey of orthohantaviruses in rodents across the tri-border region of China, Russia, and North Korea.PLoS neglected tropical diseases · 2026Article
- The origins and potential cross-species transmission of paramyxoviruses and other RNA viruses between native snakes and invasive Burmese pythons in the Florida Everglades.Journal of virology · 2026Article
- Characteristics of RNA viruses in rodents across different ecological regions of Yunnan and analysis of their evolutionary patterns and replication potential.BMC microbiology · 2026Article
- Article
434 more citing papers are in PubMed but not listed here.
Corrections and comments
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- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our understanding of the diversity and evolution of vertebrate RNA viruses is largely limited to those found in mammalian and avian hosts and associated with overt disease. Here, using a large-scale meta-transcriptomic approach, we discover 214 vertebrate-associated viruses in reptiles, amphibians, lungfish, ray-finned fish, cartilaginous fish and jawless fish. The newly discovered viruses appear in every family or genus of RNA virus associated with vertebrate infection, including those containing human pathogens such as influenza virus, the Arenaviridae and Filoviridae families, and have branching orders that broadly reflected the phylogenetic history of their hosts. We establish a long evolutionary history for most groups of vertebrate RNA virus, and support this by evaluating evolutionary timescales using dated orthologous endogenous virus elements. We also identify new vertebrate-specific RNA viruses and genome architectures, and re-evaluate the evolution of vector-borne RNA viruses. In summary, this study reveals diverse virus-host associations across the entire evolutionary history of the vertebrates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.