ArticleThe Journal of antibiotics2018
Roquefortine J, a novel roquefortine alkaloid, from the deep-sea-derived fungus Penicillium granulatum MCCC 3A00475.
Article in The Journal of antibiotics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- The Cytotoxic Activity of Secondary Metabolites from Marine-DerivedMarine drugs · 2025Review
- Discovery, Antitumor Activity, and Fermentation Optimization of Roquefortines fromMolecules (Basel, Switzerland) · 2023Article
- Structure and Biological Activity of Ergostane-Type Steroids from Fungi.Molecules (Basel, Switzerland) · 2022Review
- Cryptic Metabolites from Marine-Derived Microorganisms Using OSMAC and Epigenetic Approaches.Marine drugs · 2022Review
- Marine Indole Alkaloids-Isolation, Structure and Bioactivities.Marine drugs · 2021Review
- Structures and Biological Activities of Diketopiperazines from Marine Organisms: A Review.Marine drugs · 2021Review
- Comprehensive Overview on the Chemistry and Biological Activities of Selected Alkaloid Producing Marine-Derived Fungi as a Valuable Reservoir of Drug Entities.Biomedicines · 2021Review
- Marine-derived fungi as a source of bioactive indole alkaloids with diversified structures.Marine life science & technology · 2021Review
- An Updated Review on the Secondary Metabolites and Biological Activities ofEvidence-based complementary and alternative medicine : eCAM · 2021Review
- Antibiotics from Extremophilic Micromycetes.Russian journal of bioorganic chemistry · 2020Article
- Steroids from the Deep-Sea-Derived FungusMarine drugs · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemical investigation on the deep-sea-derived fungus Penicillium granulatum MCCC 3A00475 led to the isolation of a previously undescribed (roquefortine J, 1) and four known (2-5) roquefortine alkaloids, along with six ergosterol analogues (6-11). The planar structure of 1 was established mainly on the basis of extensive analysis of its 1D, 2D NMR, and HRESIMS spectra. The absolute configuration of 1 was determined by comparison of the calculated and experimental electronic circular dichroism spectra. Compounds 5, 6, and 7 exhibited potent anti-proliferative effects against HepG2 tumor cells with IC
Indexed as
Identifiers
29618769What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.