Evidence map›Paper›PMID 29618493›Full record

ArticleJournal of neurology, neurosurgery, and psychiatry2018

Time matters in multiple sclerosis: can early treatment and long-term follow-up ensure everyone benefits from the latest advances in multiple sclerosis?

João J Cerqueira, D Alastair S Compston, Ruth Geraldes, Mario M Rosa, Klaus Schmierer, Alan Thompson, Michela Tinelli, Jacqueline Palace

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurology, neurosurgery, and psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
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  11. A role of CD20Frontiers in immunology · 2025
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

João J CerqueiraLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.ORCID 0000-0003-3155-2775
D Alastair S CompstonDepartment of Clinical Neurosciences, Cambridge Biomedical Campus, Cambridge, UK.
Ruth GeraldesNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Mario M RosaFaculty of Medicine, University of Lisbon, Lisbon, Portugal.
Klaus SchmiererBlizard Institute, Barts and The London School of Medicine and Dentistry, London, UK.
Alan ThompsonFaculty of Brain Sciences, University College London, London, UK.
Michela TinelliLSE Enterprise, London School of Economics, London, UK.
Jacqueline PalaceNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
University of Oxford · GBBoston Biomedical (United States) · USInstitute of Cognitive and Brain Sciences · USLondon School of Economics and Political Science · GBQueen Mary University of London · GBUniversity of Lisbon · PTUniversity of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Time-to-TreatmentDisease ProgressionFollow-Up StudiesHumansImmunosuppressive AgentsMultiple SclerosisImmunosuppressive Agentsmultiple sclerosis

Identifiers

PMID29618493
PMCPMC6204938
OpenAlexW2795937082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.