Evidence map›Paper›PMID 29618474›Full record

Observational studyJournal of the American Heart Association2018

Cruciferous and Total Vegetable Intakes Are Inversely Associated With Subclinical Atherosclerosis in Older Adult Women.

Lauren C Blekkenhorst, Catherine P Bondonno, Joshua R Lewis, Richard J Woodman, Amanda Devine, Nicola P Bondonno, Wai H Lim, Kun Zhu, Lawrence J Beilin, Peter L Thompson and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Lauren C BlekkenhorstSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia lauren.blekkenhorst@research.uwa.edu.au.
Catherine P BondonnoSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
Joshua R LewisSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
Richard J WoodmanFlinders Centre for Epidemiology and Biostatistics, Flinders University, Adelaide, South Australia, Australia.
Amanda DevineSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
Nicola P BondonnoMedical School, Royal Perth Hospital Unit, University of Western Australia, Perth, Western Australia, Australia.
Wai H LimDepartment of Renal Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Kun ZhuDepartment of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Lawrence J BeilinMedical School, Royal Perth Hospital Unit, University of Western Australia, Perth, Western Australia, Australia.
Peter L ThompsonDepartment of Cardiovascular Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Richard L PrinceMedical School, Queen Elizabeth Medical Centre Unit, University of Western Australia, Nedlands, Western Australia, Australia.
Jonathan M HodgsonSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
Sir Charles Gairdner Hospital · AURoyal Perth Hospital · AUEdith Cowan University · AUUniversity of Western Australia · AUFlinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary patterns rich in fruits and vegetables are considered to reduce atherosclerotic disease presentation and are reported to be inversely associated with subclinical measures of atherosclerosis, such as carotid artery intima-media thickness (IMT) and plaque. However, the effect of vegetable intake alone, and relationships to specific types of vegetables containing different phytochemical profiles, is important. The aim of this study was to investigate the associations of total vegetable intake and specific vegetables grouped according to phytochemical constituents with common carotid artery IMT (CCA-IMT) and carotid plaque severity in a cohort of older adult women (aged ≥70 years). METHODS AND

resultsTotal vegetable intake was calculated at baseline (1998) using a validated food frequency questionnaire. Vegetable types included cruciferous, allium, yellow/orange/red, leafy green, and legumes. In 2001, CCA-IMT (n=954) and carotid focal plaque (n=968) were assessed using high-resolution B-mode carotid ultrasonography. Mean (SD) total vegetable intake was 199.9 (78.0) g/d. Women consuming ≥3 servings of vegetables each day had ≈4.6% to 5.0% lower mean CCA-IMT (

conclusionsIncreasing vegetables in the diet with a focus on consuming cruciferous vegetables may have benefits for the prevention of subclinical atherosclerosis in older adult women. CLINICAL

trial registrationURL: http://www.anzctr.org.au. Unique identifier: ACTRN12615000750583.

Indexed as

DietVegetablesAgedCarotid Artery, CommonCarotid Artery DiseasesCarotid Intima-Media ThicknessFemaleFollow-Up StudiesHumansNutritive ValuePlaque, AtheroscleroticPrognosisRetrospective StudiesRisk Factorsatherosclerosiscarotid intima‐media thicknesscarotid plaquecruciferousvegetables

Identifiers

PMID29618474
PMCPMC6015430
OpenAlexW2795722655

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.