Evidence map›Paper›PMID 29617951›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018

Non-mumps Viral Parotitis During the 2014-2015 Influenza Season in the United States.

Lina I Elbadawi, Pamela Talley, Melissa A Rolfes, Alexander J Millman, Erik Reisdorf, Natalie A Kramer, John R Barnes, Lenee Blanton, Jaime Christensen, Stefanie Cole and 27 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Case Report of Herpes Zoster Ophthalmicus with Concurrent Parotitis.Journal of education & teaching in emergency medicine · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Is Parotitis One More Complication of Influenza? The Ongoing Challenge of Determining Causal Associations.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  20. Influenza-Associated Parotitis During the 2014-2015 Influenza Season in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

37 authors at 10 institutions in 1 country.

Lina I ElbadawiEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia.
Pamela TalleyEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia.
Melissa A RolfesEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia.
Alexander J MillmanEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia.
Erik ReisdorfWisconsin State Laboratory of Hygiene, Madison.
Natalie A KramerInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
John R BarnesInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Lenee BlantonInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jaime ChristensenMinnesota Department of Health, St. Paul, Atlanta, Georgia.
Stefanie ColeMichigan Department of Health and Human Services, Lansing.
Tonya DanzWisconsin State Laboratory of Hygiene, Madison.
John J DreisigNew Hampshire Division of Public Health Services, Concord.
Rebecca GartenInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Thomas HauptBureau of Communicable Diseases, Wisconsin Division of Public Health, Madison.
Beth M IsaacNew York City Department of Health & Mental Hygiene Bureau of Immunization, Queens.
Mary Anne JacksonChildren's Mercy Hospital, Kansas City, Missouri.
Anna KocharianBureau of Communicable Diseases, Wisconsin Division of Public Health, Madison.
Daniel LeiferInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Karen MartinMinnesota Department of Health, St. Paul, Atlanta, Georgia.
Lisa McHughCommunicable Disease Service, New Jersey Department of Health, Trenton.
Rebecca J McNallDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jennifer PalmMinnesota Department of Health, St. Paul, Atlanta, Georgia.
Kay W RadfordDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Sara RobinsonMaine Center for Disease Control and Prevention, Maine Department of Health and Human Services, Augusta.
Jennifer B RosenNew York City Department of Health & Mental Hygiene Bureau of Immunization, Queens.
Senthilkumar K SakthivelDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Peter ShultWisconsin State Laboratory of Hygiene, Madison.
Anna K StrainMinnesota Department of Health, St. Paul, Atlanta, Georgia.
George TurabelidzeMissouri Department of Health and Senior Services, St. Louis.
Lori A WebberMaine Center for Disease Control and Prevention, Maine Department of Health and Human Services, Augusta.
Meghan Pearce WeinbergEpidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia.
David E WentworthInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Brett L WhitakerDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Lyn FinelliInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Michael A JhungInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Ruth LynfieldMinnesota Department of Health, St. Paul, Atlanta, Georgia.
Jeffrey P DavisBureau of Communicable Diseases, Wisconsin Division of Public Health, Madison.
Centers for Disease Control and Prevention · USMinnesota Department of Health · USWisconsin Division of Public Health · USEpidemic Intelligence Service · USNew York City Department of Health and Mental Hygiene · USState of Maine Department of Health and Human Services · USMercy Hospital · USMichigan Department of Health and Human Services · USMissouri Department of Health and Senior Services · USNew Jersey Department of Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Background: During the 2014-2015 US influenza season, 320 cases of non-mumps parotitis (NMP) among residents of 21 states were reported to the Centers for Disease Control and Prevention (CDC). We conducted an epidemiologic and laboratory investigation to determine viral etiologies and clinical features of NMP during this unusually large occurrence. Methods: NMP was defined as acute parotitis or other salivary gland swelling of >2 days duration in a person with a mumps- negative laboratory result. Using a standardized questionnaire, we collected demographic and clinical information. Buccal samples were tested at the CDC for selected viruses, including mumps, influenza, human parainfluenza viruses (HPIVs) 1-4, adenoviruses, cytomegalovirus, Epstein-Barr virus (EBV), herpes simplex viruses (HSVs) 1 and 2, and human herpes viruses (HHVs) 6A and 6B. Results: Among the 320 patients, 65% were male, median age was 14.5 years (range, 0-90), and 67% reported unilateral parotitis. Commonly reported symptoms included sore throat (55%) and fever (48%). Viruses were detected in 210 (71%) of 294 NMP patients with adequate samples for testing, ≥2 viruses were detected in 37 samples, and 248 total virus detections were made among all samples. These included 156 influenza A(H3N2), 42 HHV6B, 32 EBV, 8 HPIV2, 2 HPIV3, 3 adenovirus, 4 HSV-1, and 1 HSV-2. Influenza A(H3N2), HHV6B, and EBV were the most frequently codetected viruses. Conclusions: Our findings suggest that, in addition to mumps, clinicians should consider respiratory viral (influenza) and herpes viral etiologies for parotitis, particularly among patients without epidemiologic links to mumps cases or outbreaks.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansInfantInfant, NewbornInfluenza, HumanMaleMiddle AgedMumpsParotitisPharyngitis

Identifiers

PMID29617951
PMCPMC6240917
OpenAlexW2794709786

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.