Evidence map›Paper›PMID 29617578›Full record

ReviewThe New England journal of medicine2018

The Key Role of Epigenetics in Human Disease Prevention and Mitigation.

Andrew P Feinberg

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The New England journal of medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 313 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
313citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03882684 unknown statusnot on this map

Role of Genomic Imprinting in Cancer Diagnosis

TypeobservationalSponsorChinese Alliance Against Lung CancerRan2017 to 2020Enrolled1,500ConditionsEarly Diagnosis, Cancer, Biomarker, Genomic ImprintingArmsIn-situ imprinting detection
NCT03923335 not yet recruitingnot on this mapstarted 2019, after this paper: background citation

The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer

TypeobservationalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2019 to 2026Enrolled287ConditionsColorectal NeoplasmsArmsDNA methylation detection
3 · Its place in the literature

Who cites it

313 citing papers in PubMed, 1 synthesis or guideline pooled it.

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253 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Andrew P FeinbergFrom the Department of Medicine, Johns Hopkins University School of Medicine, the Department of Biomedical Engineering, Whiting School of Engineering, and the Department of Mental Health, Johns Hopkins Bloomberg School of Public Health - all in Baltimore.

Funding

MOLECULAR PATHOLOGY OF WILMS TUMOR RELATED GENES 11PR01CA054358 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ANDREW P. FEINBERG · 1991 to 2026
$5.5M
NCI NIH HHS R01 CA054358
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epigenesis, GeneticPreventive MedicineChromatinDNA MethylationEpigenomicsGene-Environment InteractionGenome-Wide Association StudyHumansNeoplasmsProtein Processing, Post-TranslationalRisk AssessmentChromatin

Identifiers

PMID29617578
PMCPMC11567374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.