Evidence map›Paper›PMID 29617551›Full record

ArticleEnvironmental science & technology2018

Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca

Jing Zheng, Shaun M K McKinnie, Abrahim El Gamal, Wei Feng, Yao Dong, Vinayak Agarwal, William Fenical, Abdhesh Kumar, Zhengyu Cao, Bradley S Moore and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Environmental science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  4. Toxicity Assessment of Octachlorostyrene in Human Liver Carcinoma (HepG2) Cells.International journal of environmental research and public health · 2022
    Article
  5. Marine and Anthropogenic Bromopyrroles Alter Cellular CaEnvironmental science & technology · 2021
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jing ZhengDepartment of Molecular Biosciences, School of Veterinary Medicine , University of California , Davis , California 95616 , United States.
Shaun M K McKinnieCenter for Oceans and Human Health, Scripps Institution of Oceanography & Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093-0021 , United States.
Abrahim El GamalCenter for Oceans and Human Health, Scripps Institution of Oceanography & Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093-0021 , United States.
Wei FengDepartment of Molecular Biosciences, School of Veterinary Medicine , University of California , Davis , California 95616 , United States.
Yao DongDepartment of Molecular Biosciences, School of Veterinary Medicine , University of California , Davis , California 95616 , United States.
Vinayak Agarwal
Abdhesh KumarCenter for Oceans and Human Health, Scripps Institution of Oceanography & Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093-0021 , United States.
Zhengyu CaoDepartment of Molecular Biosciences, School of Veterinary Medicine , University of California , Davis , California 95616 , United States.ORCID 0000-0002-2692-2949
Bradley S MooreCenter for Oceans and Human Health, Scripps Institution of Oceanography & Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093-0021 , United States.ORCID 0000-0002-4652-1253
Isaac N PessahDepartment of Molecular Biosciences, School of Veterinary Medicine , University of California , Davis , California 95616 , United States.ORCID 0000-0002-8149-588X
Scripps Institution of Oceanography · USUniversity of California, Davis · USChina Pharmaceutical University · CN

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 1990 to 2026
$40.5M
UC Davis Center for Children's Environmental Health (CCEH)P01ES011269 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI VAN DE WATER, JUDY A. · 2001 to 2018
$12.5M
Molecular and Cellular Basis of PCB Developmental Neurotoxicity: ViCTER supplementR01ES014901 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HANS-JOACHIM LEHMLER, Pamela J Lein · 2009 to 2026
$9.3M
Sources and Sins of Halogenated Organic Compounds in the Marine EnvironmentP01ES021921 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOORE, BRADLEY S · 2012 to 2016
$1.9M
Understanding natural production of polybrominated toxins and pollutantsR00ES026620 · NIEHS · GEORGIA INSTITUTE OF TECHNOLOGY · PI AGARWAL, VINAYAK · 2017 to 2019
$747k
NIEHS NIH HHS P01 ES011269NIEHS NIH HHS P01 ES021921NIEHS NIH HHS P30 ES005605NIEHS NIH HHS P42 ES004699NIEHS NIH HHS R00 ES026620NIEHS NIH HHS R01 ES014901
6 · The paper itself

Abstract

Contemporary sources of organohalogens produced as disinfection byproducts (DBPs) are receiving considerable attention as emerging pollutants because of their abundance, persistence, and potential to structurally mimic natural organohalogens produced by bacteria that serve signaling or toxicological functions in marine environments. Here, we tested 34 organohalogens from anthropogenic and marine sources to identify compounds active toward ryanodine receptor (RyR1), known toxicological targets of non-dioxin-like polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs). [

Indexed as

Environmental PollutantsPolychlorinated BiphenylsDisinfectionEndoplasmic Reticulum StressHalogenated Diphenyl EthersRyanodine Receptor Calcium Release ChannelEnvironmental PollutantsHalogenated Diphenyl EthersPolychlorinated BiphenylsRyanodine Receptor Calcium Release Channel

Identifiers

PMID29617551
PMCPMC6195434
OpenAlexW2795981252

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.