Evidence map›Paper›PMID 29617475›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo

ULTRASONOGRAPHIC MARKERS OF CARDIOVASCULAR DISEASE RISK IN OBESE CHILDREN.

Karla Cristina Malta Costa, Luiz Antonio Del Ciampo, Patrícia Silveira Silva, Jailson Costa Lima, Wellington de Paula Martins, Carlos Alberto Nogueira de Almeida

Erratum issuedAbstract read
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Karla Cristina Malta CostaDepartamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Luiz Antonio Del CiampoDepartamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Patrícia Silveira SilvaDepartamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Jailson Costa LimaDepartamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Wellington de Paula MartinsDepartamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Carlos Alberto Nogueira de AlmeidaDepartamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate whether the obesity alters ultrasonographical markers of metabolic and cardiovascular disease risk in children.

methodsA cross-sectional study evaluated 80 children aged between 6 and 10 years, comparing 40 obese with 40 normal children. The following parameters were assessed: weight; height; body mass index; arterial blood pressure; body fat; basal metabolic rate; HDL-cholesterol, LDL-cholesterol and total cholesterol; fasting insulin and glucose; quantitative insulin sensitivity check index (QUICKI); homeostasis model of assessment - insulin resistance (HOMA-IR); basal diameter of the brachial artery; brachial artery flow mediated dilation (FMD) and of pulsatility index change (PI-C).

resultsSignificant differences were observed between obese vs. non-obese children: systolic blood pressure (97.7±8.4 vs. 89.0±5.8 mmHg; p<0.01), diastolic blood pressure (64.3±7.9 vs. 52.9±5.1 mmHg; p<0.01), proportion of body fat (45.1±5.9 vs. 21.3±6.0%; p<0.01), basal metabolic rate (1216.1±102.1 vs. 1072.9±66.4 Kcal; p<0.01), total cholesterol (164.7±25.2 vs. 153.4±15.8 mg/dL; p=0.03), fasting insulin (7.1±5.2 vs. 2.8±1.8 pIU/mL; p<0.01), HOMA-IR (1.5±1.1 vs. 0.6±0.4; p<0.01), basal diameter of the brachial artery (2.5±0.3 vs. 2.1±0.3 mm; p<0.01); PI-C (-15.5±27.2 vs. -31.9±15.5%; p<0.01), decreased QUICKI (0.4±0.05 vs. 0.4±0.03; p<0.01), and FMD (6.6±3.2 vs. 15.6±7.3%; p<0.01).

conclusionsObesity worsens ultrasonographical and laboratorial markers of metabolic and cardiovascular disease risk in children.

Indexed as

Cardiovascular DiseasesChildCross-Sectional StudiesHumansMetabolic SyndromePediatric ObesityRisk FactorsUltrasonography

Identifiers

PMID29617475
PMCPMC6038792

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.