ArticlePloS one2018
Magnetic resonance imaging does not reveal structural alterations in the brain of grapheme-color synesthetes.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Brain Folding Trajectories in Amyotrophic Lateral Sclerosis.Human brain mapping · 2026Article
- Developmental trajectories of gyrification and sulcal morphometrics in children and adolescents at high familial risk for bipolar disorder or schizophrenia.Developmental cognitive neuroscience · 2025Article
- Investigation of the relationship between neuroplasticity and grapheme-color synesthesia.Frontiers in neuroscience · 2024Article
- Sulcal Morphometry Predicts Mild Cognitive Impairment Conversion to Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Article
- Synesthesia does not help to recover perceptual dominance following flash suppression.Scientific reports · 2021Article
- Predicting Progression from Mild Cognitive Impairment to Alzheimer's Disease using MRI-based Cortical Features and a Two-State Markov Model.Proceedings. IEEE International Symposium on Biomedical Imaging · 2021Article
- Stochastic resonance model of synaesthesia.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- Double-blind study of visual imagery in grapheme-color synesthesia.Cortex; a journal devoted to the study of the nervous system and behavior · 2019Article
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Authors and funding
3 authors.
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Abstract
Several publications have reported structural changes in the brain of synesthetes compared to controls, either local differences or differences in connectivity. In the present study, we pursued this quest for structural brain differences that might support the subjective experience of synesthesia. In particular, for the first time in this field, we investigated brain folding in comparing 45 sulcal shapes in each hemisphere of control and grapheme-color synesthete populations. To overcome flaws relative to data interpretation based only on p-values, common in the synesthesia literature, we report confidence intervals of effect sizes. Moreover, our statistical maps are displayed without introducing the classical, but misleading, p-value level threshold. We adopt such a methodological procedure to facilitate appropriate data interpretation and promote the "New Statistics" approach. Based on structural or diffusion magnetic resonance imaging data, we did not find any strong cerebral anomaly, in sulci, tissue volume, tissue density or fiber organization that could support synesthetic color experience. Finally, by sharing our complete datasets, we strongly support the multi-center construction of a sufficient large dataset repository for detecting, if any, subtle brain differences that may help understanding how a subjective experience, such as synesthesia, is mentally constructed.
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