Evidence map›Paper›PMID 29617310›Full record

ArticleNutrients2018

Protective Effects of Ellagitannin-Rich Strawberry Extracts on Biochemical and Metabolic Disturbances in Rats Fed a Diet High in Fructose.

Bartosz Fotschki, Jerzy Juśkiewicz, Krzysztof Kołodziejczyk, Adam Jurgoński, Monika Kosmala, Joanna Milala, Katarzyna Ognik, Zenon Zduńczyk

Open access · goldAbstract readComparative Study
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bartosz FotschkiInstitute of Animal Reproduction and Food Research, Division of Food Science, Tuwima 10, 10-748 Olsztyn, Poland. b.fotschki@pan.olsztyn.pl.ORCID 0000-0002-9727-7481
Jerzy JuśkiewiczInstitute of Animal Reproduction and Food Research, Division of Food Science, Tuwima 10, 10-748 Olsztyn, Poland. j.juskiewicz@pan.olsztyn.pl.ORCID 0000-0003-0068-5970
Krzysztof KołodziejczykInstitute of Food Technology and Analysis, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland. krzysztof.kolodziejczyk@p.lodz.pl.
Adam JurgońskiInstitute of Animal Reproduction and Food Research, Division of Food Science, Tuwima 10, 10-748 Olsztyn, Poland. a.jurgonski@pan.olsztyn.pl.ORCID 0000-0003-3524-3259
Monika KosmalaInstitute of Food Technology and Analysis, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland. monika.kosmala@p.lodz.pl.ORCID 0000-0002-9018-3028
Joanna MilalaInstitute of Food Technology and Analysis, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland. joanna.milala@p.lodz.pl.
Katarzyna OgnikDepartment of Biochemistry and Toxicology, Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences, 20-950 Lublin, Poland. kasiaognik@poczta.fm.
Zenon ZduńczykInstitute of Animal Reproduction and Food Research, Division of Food Science, Tuwima 10, 10-748 Olsztyn, Poland. z.zdunczyk@pan.olsztyn.pl.
InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences · PLLodz University of Technology · PLUniversity of Life Sciences in Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study compares the effects of two dietary strawberry extracts rich in monomeric (ME) or dimeric (DE) ellagitannins (ETs) on gastrointestinal, blood and tissue biomarkers in Wistar rats fed high-fructose diets. Both strawberry extracts beneficially affect the antioxidant status and lipid profile of the liver and serum. The ME extract shows a greater ability to inhibit lipid peroxidation in kidneys, more effectively decreases serum and liver triglycerides, and exerts greater anti-inflammatory effects in blood serum than the DE extract. The DE extract significantly reduces the activity of microbial enzymes in the cecum. These effects might be associated with higher cecum and urine levels of ET metabolites in rats fed with ME than in rats fed with DE. In conclusion, the diet-induced fructose-related disturbances observed in biochemical parameters are regulated by both extracts; nevertheless, the beneficial effects of the ME extract are mostly associated with systemic parameters, while those of the DE extracts are associated with local microbial activity.

Indexed as

FragariaAnimalsAnti-Inflammatory AgentsAntioxidantsBiomarkersCecumDietary SugarsFructoseFruitGastrointestinal MicrobiomeHydrolyzable TanninsLipid PeroxidationLipidsLiverMaleOxidative StressAnti-Inflammatory AgentsAntioxidantsBiomarkersDietary SugarsellagitanninFructoseHydrolyzable TanninsLipidsPlant Extractsglutathioneinflammatory cytokinesmicrobiota activitymonomeric ellagitanninsnasutin A

Identifiers

PMID29617310
PMCPMC5946230
OpenAlexW2795446002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.