Evidence map›Paper›PMID 29617183›Full record

SynthesisHuman vaccines & immunotherapeutics2018

Measuring trust in vaccination: A systematic review.

Heidi J Larson, Richard M Clarke, Caitlin Jarrett, Elisabeth Eckersberger, Zachary Levine, Will S Schulz, Pauline Paterson

3 registry-linked trialsAbstract readSystematic Review
In one paragraph

Synthesis in Human vaccines & immunotherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 377 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
377citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06290206 nacompletednot on this mapstarted 2024, after this paper: background citation

PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - BootCamp Translation

TypeinterventionalSponsorUniversity of UtahRan2024 to 2024Enrolled18ConditionsHPV Vaccination, Vaccine, Uptake, VaccinationArmsPREVENT - BCT
NCT06738355 nacompletednot on this mapstarted 2025, after this paper: background citation

PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Pilot Trial

TypeinterventionalSponsorUniversity of UtahRan2025 to 2025Enrolled335ConditionsHPV Vaccination, Uptake Vaccination, Series CompletionArmsPREVENT
NCT07217145 phase3active not recruitingnot on this mapstarted 2025, after this paper: background citation

PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Randomized Controlled Trial (RCT)

TypeinterventionalSponsorUniversity of UtahRan2025 to 2027Enrolled1,455ConditionsHPV Vaccination, Uptake Vaccination, Series CompletionArmsPREVENT
3 · Its place in the literature

Who cites it

377 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. "Vaccinating your child during an emergency is more important than ever": a randomised controlled trial on message framing among Ukrainian refugees in Poland, 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Trial
  5. Article
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317 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Heidi J Larsona Department of Infectious Disease Epidemiology , The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , United Kingdom.
Richard M Clarkea Department of Infectious Disease Epidemiology , The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , United Kingdom.
Caitlin Jarretta Department of Infectious Disease Epidemiology , The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , United Kingdom.
Elisabeth Eckersbergerd Ipas , Chapel Hill , North Carolina , USA.
Zachary Levinea Department of Infectious Disease Epidemiology , The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , United Kingdom.
Will S Schulza Department of Infectious Disease Epidemiology , The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , United Kingdom.
Pauline Patersona Department of Infectious Disease Epidemiology , The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccine acceptance depends on public trust and confidence in the safety and efficacy of vaccines and immunization, the health system, healthcare professionals and the wider vaccine research community. This systematic review analyses the current breadth and depth of vaccine research literature that explicitly refers to the concept of trust within their stated aims or research questions. After duplicates were removed, 19,643 articles were screened by title and abstract. Of these 2,779 were screened by full text, 35 of which were included in the final analysis. These studies examined a range of trust relationships as they pertain to vaccination, including trust in healthcare professionals, the health system, the government, and friends and family members. Three studies examined generalized trust. Findings indicated that trust is often referred to implicitly (19/35), rather than explicitly examined in the context of a formal definition or discussion of the existing literature on trust in a health context. Within the quantitative research analysed, trust was commonly measured with a single-item measure (9/25). Only two studies used validated multi-item measures of trust. Three studies examined changes in trust, either following an intervention or over the course of a pandemic. The findings of this review indicate a disconnect between the current vaccine hesitancy research and the wider health-related trust literature, a dearth in research on trust in low and middle-income settings, a need for studies on how trust levels change over time and investigations on how resilience to trust-eroding information can be built into a trustworthy health system.

Indexed as

Patient Acceptance of Health CareTrustCommunicationFemaleHealth Knowledge, Attitudes, PracticeHealth PersonnelHumansMalePregnancyVaccinationVaccination RefusalVaccinesVaccinesconfidenceimmunization/immunisationTrustvaccinationvaccines

Identifiers

PMID29617183
PMCPMC6067893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.