Evidence map›Paper›PMID 29617130›Full record

ArticleThe journal of physical chemistry. B2018

Structure and Dynamics of DNA and RNA Double Helices Obtained from the CCG and GGC Trinucleotide Repeats.

Feng Pan, Viet Hoang Man, Christopher Roland, Celeste Sagui

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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  13. Targeted Oligonucleotides for Treating Neurodegenerative Tandem Repeat Diseases.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Feng PanDepartment of Physics , North Carolina State University , Raleigh , North Carolina 27695-8202 , United States.
Viet Hoang ManDepartment of Physics , North Carolina State University , Raleigh , North Carolina 27695-8202 , United States.
Christopher RolandDepartment of Physics , North Carolina State University , Raleigh , North Carolina 27695-8202 , United States.
Celeste SaguiDepartment of Physics , North Carolina State University , Raleigh , North Carolina 27695-8202 , United States.ORCID 0000-0002-2750-5186
North Carolina State University · US

Funding

Trinucleotide Repeats: Atypical Structures, Diseases, and EvolutionR01GM118508 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAGUI, MARIA CELESTE · 2016 to 2019
$1.1M
NIGMS NIH HHS R01 GM118508
6 · The paper itself

Abstract

Expansions of both GGC and CCG sequences lead to a number of expandable, trinucleotide repeat (TR) neurodegenerative diseases. Understanding of these diseases involves, among other things, the structural characterization of the atypical DNA and RNA secondary structures. We have performed molecular dynamics simulations of (GCC)

Indexed as

Molecular Dynamics SimulationNucleic Acid ConformationTrinucleotide RepeatsDNARNADNARNA

Identifiers

PMID29617130
PMCPMC6475210
OpenAlexW2795706756

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.