ArticleJournal of the American Chemical Society2018
Feedback-Induced Temporal Control of "Breathing" Polymersomes To Create Self-Adaptive Nanoreactors.
Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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Who cites it
65 citing papers in PubMed.
- The Power of Tiny Spaces.JACS Au · 2026Review
- Wavelength-dependent feedback behavior in light-gated polymersome nanoreactors.Nature communications · 2026Article
- Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications.Angewandte Chemie (International ed. in English) · 2026Review
- Enhanced enzyme stability at the interphase of water-oil for continuous-flow olefin epoxidation.Nature communications · 2025Article
- Membrane Transport Modulates the pH-Regulated Feedback of an Enzyme Reaction Confined within Lipid Vesicles.ACS nano · 2025Article
- Unveiling the influence of oxygen on drug release dynamics in semipermeable polymersomes.Angewandte Chemie (International ed. in English) · 2025Article
- Transient transition from Stable to Dissipative Assemblies in Response to the Spatiotemporal Availability of a Chemical Fuel.Angewandte Chemie (International ed. in English) · 2025Article
- Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport.Nature chemistry · 2025Article
- Growing functional artificial cytoskeletons in the viscoelastic confinement of DNA synthetic cells.Nature chemical engineering · 2025Article
- Biomimetic Materials to Fabricate Artificial Cells.Chemical reviews · 2024Review
- Boosting Microfluidic Enzymatic Cascade Reactions with pH-Responsive Polymersomes by Spatio-Chemical Activity Control.Small methods · 2024Article
- Microfluidics-Assisted Polymer Vesicle Budding in Emulsion Systems: A Promising Approach for the Preparation and Application of Polymer Vesicles.Molecules (Basel, Switzerland) · 2024Article
- Kinetically Controlled and Nonequilibrium Assembly of Block Copolymers in Solution.Journal of the American Chemical Society · 2024Review
- Glycooligomer-Functionalized Catalytic Nanocompartments Co-Loaded with Enzymes Support Parallel Reactions and Promote Cell Internalization.Biomacromolecules · 2024Article
- Cupric-polymeric nanoreactors integrate into copper metabolism to promote chronic diabetic wounds healing.Materials today. Bio · 2024Article
- Using a biocatalyzed reaction cycle for transient and pH-dependent host-guest supramolecular hydrogels.Journal of materials chemistry. B · 2024Article
- Light-Triggered Inflation of Microdroplets.Chemistry of materials : a publication of the American Chemical Society · 2024Article
- Dampened Transient Actuation of Hydrogels Autonomously Controlled by pH-Responsive Bicontinuous Nanospheres.ACS applied materials & interfaces · 2024Article
- In Vitro Detection of Lactate and Uric Acid Based on Adaptive Graphene Oxide Membranes.Small science · 2024Article
- Exploring Emergent Properties in Enzymatic Reaction Networks: Design and Control of Dynamic Functional Systems.Chemical reviews · 2024Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we present the development of self-regulated "breathing" polymersome nanoreactors that show temporally programmable biocatalysis induced by a chemical fuel. pH-sensitive polymersomes loaded with horseradish peroxidase (HRP) and urease were developed. Addition of an acidic urea solution ("fuel") endowed the polymersomes with a transient size increase and permeability enhancement, driving a temporal "ON" state of the HRP enzymatic catalysis; subsequent depletion of fuel led to shrinking of the polymersomes, resulting in the catalytic "OFF" state. Moreover, the nonequilibrium nanoreactors could be reinitiated several cycles as long as fuel was supplied. This feedback-induced temporal control of catalytic activity in polymersome nanoreactors provides a platform for functional nonequilibrium systems as well as for artificial organelles with precisely controlled adaptivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.