ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Vitamin C inhibits crystallization of struvite from artificial urine in the presence of Pseudomonas aeruginosa.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- The Role of Vitamins in Pediatric Urinary Tract Infection: Mechanisms and Integrative Strategies.Biomolecules · 2025Review
- Dissolution of struvite stones with ascorbic acid.Urology case reports · 2025Article
- The Multidisciplinary Approach in the Management of Patients with Kidney Stone Disease-A State-of-the-Art Review.Nutrients · 2024Review
- The key role of major and trace elements in the formation of five common urinary stones.BMC urology · 2024Article
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Kidney Stone Prevention.Advances in nutrition (Bethesda, Md.) · 2023Review
- Small organic molecules containing amorphous calcium phosphate: synthesis, characterization and transformation.Frontiers in bioengineering and biotechnology · 2023Article
- Malonate utilization by Pseudomonas aeruginosa affects quorum-sensing and virulence and leads to formation of mineralized biofilm-like structures.Molecular microbiology · 2021Article
- [A severe course of struvite stones in the upper and lower urinary tract of a 52-year-old man].Der Urologe. Ausg. A · 2020Article
- Microstructural diversity of gallstones revealed by spectral microanalyses and their association with hepatic parameters.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFormation of struvite stones is associated with urinary tract infection by urease-producing bacteria. Biogenic crystal growth in natural and synthetic materials is regulated by the action of inhibitors, ranging from small ions, molecules to large macromolecules. MATERIALS AND
methodsWe report the dynamics of in vitro crystallization of struvite in presence of vitamin C in synthetic urine using single diffusion gel growth technique. Sodium metasilicate gel of specific gravity 1.05 and the aqueous solution of ammonium dihydrogen phosphate were used as the medium for growing the struvite crystals. The crystallization process was induced by a urease positive struvite stone associated Pseudomonas aeruginosa to mimic the infection leading to stone formation. The grown crystals were characterized by ATR-FTIR and powder XRD. The surface morphology was analysed through FE-SEM for comparison between treatments.
resultsWe observed decrease in number, dimension, and growth rate of struvite crystals with the increasing concentrations of vitamin C. Crystals displayed well-defined faces and dendritic morphology of struvite in both control and biogenic systems.
conclusionThe results strongly suggest that, vitamin C can modulate the formation of struvite crystals in the presence of uropathogenic bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.