ReviewPhysiology (Bethesda, Md.)2018
Is Adenosine Action Common Ground for NREM Sleep, Torpor, and Other Hypometabolic States?
Review in Physiology (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Article
- Biological Mechanisms Balancing Torpor and Reproduction in Mammals.Endocrinology · 2025Review
- Altered circadian rhythm, sleep, andProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Adenosine and P1 receptors: Key targets in the regulation of sleep, torpor, and hibernation.Frontiers in pharmacology · 2023Review
- The integrative process promoted by EMDR in dissociative disorders: neurobiological mechanisms, psychometric tools, and intervention efficacy on the psychological impact of the COVID-19 pandemic.Frontiers in psychology · 2023Review
- The burst of electrophysiological signals in the suprachiasmatic nucleus of mouse during the arousal detected by microelectrode arrays.Frontiers in bioengineering and biotechnology · 2022Article
- Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder.PloS one · 2021Article
- Editorial: The Integrative Physiology of Metabolic Downstates.Frontiers in physiology · 2021Article
- Turn it off and on again: characteristics and control of torpor.Wellcome open research · 2021Review
- The physiological signature of daily torpor is not orexin dependent.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2020Article
- Eat, sleep, repeat: the role of the circadian system in balancing sleep-wake control with metabolic need.Current opinion in physiology · 2020Review
- Shallow metabolic depression and human spaceflight: a feasible first step.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Activation of neuronal adenosine A1 receptors causes hypothermia through central and peripheral mechanisms.PloS one · 2020Article
- A Temporal Examination of Cytoplasmic CaFrontiers in physiology · 2020Article
- Physiology and effects of nucleosides in mice lacking all four adenosine receptors.PLoS biology · 2019Article
- Changes in blood glucose as a function of body temperature in laboratory mice: implications for daily torpor.American journal of physiology. Endocrinology and metabolism · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
This review compares two states that lower energy expenditure: non-rapid eye movement (NREM) sleep and torpor. Knowledge on mechanisms common to these states, and particularly on the role of adenosine in NREM sleep, may ultimately open the possibility of inducing a synthetic torpor-like state in humans for medical applications and long-term space travel. To achieve this goal, it will be important, in perspective, to extend the study to other hypometabolic states, which, unlike torpor, can also be experienced by humans.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.