Evidence map›Paper›PMID 29616707›Full record

ArticleThe journal of prevention of Alzheimer's disease2018

Adherence to the Mediterranean Diet Is not Related to Beta-Amyloid Deposition: Data from the Women's Healthy Ageing Project.

E Hill, C Szoeke, L Dennerstein, S Campbell, P Clifton

Open access · diamondAbstract read
In one paragraph

Article in The journal of prevention of Alzheimer's disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  11. Dietary patterns and β-amyloid deposition in aging Australian women.Alzheimer's & dementia (New York, N. Y.) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

E HillLaura Bonner, PhD, GRECC-S-182, VA Puget Sound Healthcare System, 1660 S. Columbian Way, Seattle, WA 98108, 206-550-1681, lmebonner@live.com.
C Szoeke
L Dennerstein
S Campbell
P Clifton
University of Melbourne · AUMelbourne Health · AUUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResearch has indicated the neuroprotective potential of the Mediterranean diet. Adherence to the Mediterranean diet has shown preventative potential for Alzheimer's disease incidence and prevalence, yet few studies have investigated the impact of Mediterranean diet adherence on the hallmark protein; beta-amyloid.

objectivesTo investigate the association between Mediterranean diet adherence and beta-amyloid deposition in a cohort of healthy older Australian women.

designThis study was a cross-sectional investigation of participants from the longitudinal, epidemiologically sourced Women's Healthy Ageing Project which is a follow-up of the Melbourne Women's Midlife Health Project.

settingAssessments were conducted at the Centre for Medical Research, Royal Melbourne Hospital in Melbourne, Australia. F-18 Florbetaben positron emission tomography scanning was conducted at the Austin Centre for PET in Victoria, Australia.

participantsOne hundred and eleven Women's Healthy Ageing Project participants were included in the study. MEASUREMENTS: Mediterranean diet adherence scores for all participants were calculated from the administration of a validated food frequency questionnaire constructed by the Cancer Council of Victoria. Beta-amyloid deposition was measured using positron emission tomography standardised uptake value ratios.

resultsGamma regression analysis displayed no association between Mediterranean diet adherence and beta-amyloid deposition. This result was consistent across APOE-ε4 +/- cohorts and with the inclusion of covariates such as age, education, body mass index and cognition.

conclusionsThis study found no association between adherence to the Mediterranean diet and beta-amyloid deposition in a cohort of healthy Australian women.

Indexed as

Patient ComplianceAgedAmyloid beta-PeptidesAniline CompoundsBrainCross-Sectional StudiesDiet, MediterraneanFemaleFunctional NeuroimagingHealthy VolunteersHumansNeuropsychological TestsPositron-Emission TomographyStilbenesWomen's Health4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbeneAmyloid beta-PeptidesAniline CompoundsStilbenesAlzheimer’s diseasebeta-AmyloiddepositionDietMediterranean diet

Identifiers

PMID29616707
PMCPMC12280801
OpenAlexW2791336718

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.