ReviewMedical oncology (Northwood, London, England)2018
De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients.
Review in Medical oncology (Northwood, London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Controversial issues in radiotherapy after breast-conserving surgery for early breast cancer in older patients: a systematic review.Journal of radiation research · 2018Pooled it
- Integrating Tumor-Intrinsic and Immunologic Factors to Identify Immunogenic Breast Cancers from a Low-Risk Cohort: Results from the Randomized SweBCG91RT Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023Trial
- Risk of myocardial infarction and stroke after breast cancer: an analysis of a population of 1.3 million women from North-West Italy.Breast cancer research and treatment · 2026Article
- Hype or hope? A review of challenges in balancing tumor control and treatment toxicity in breast cancer from the perspective of the radiation oncologist.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024Review
- Survival analysis of palliative radiotherapy in patients with HER-2+ metastatic breast cancer.Frontiers in endocrinology · 2023Article
- Hypofractionation and Concomitant Boost in Ductal Carcinoma In Situ (DCIS): Analysis of a Prospective Case Series with Long-Term Follow-Up.Life (Basel, Switzerland) · 2022Article
- Comparison of Efficacy and Psychology of Breast-Conserving Surgery and Modified Radical Mastectomy on Patients with Early Breast Cancer under Graded Nursing.Computational and mathematical methods in medicine · 2022Article
- A patient decision aid for breast cancer patients deciding on their radiation treatment, no change in decisional conflict but better informed choices.Technical innovations & patient support in radiation oncology · 2021Article
- Nomogram for the personalisation of radiotherapy treatments in breast cancer patients.Breast (Edinburgh, Scotland) · 2021Article
- Clinical Relevance of Tubular Breast Carcinoma: Large Retrospective Study and Meta-Analysis.Frontiers in oncology · 2021Article
- Older age and comorbidity in breast cancer: is RT alone the new therapeutic frontier?Journal of cancer research and clinical oncology · 2020Article
- Accelerated Partial Breast Irradiation: A New Standard of Care?Breast care (Basel, Switzerland) · 2020Review
- Omission of postoperative radiation after breast conserving surgery: A progressive paradigm shift towards precision medicine.Clinical and translational radiation oncology · 2020Review
- Suggestions for Radiation Oncologists during the COVID-19 Pandemic.BioMed research international · 2020Review
- Do hypofraction and large breast size reciprocally fit in breast cancer radiotherapy?Annals of translational medicine · 2019Article
- Adjuvant chemotherapy for node negative, high Recurrence ScoreNPJ breast cancer · 2019Article
- Simulation modeling for clinical trials evaluating radiotherapy omission in low-risk early breast cancer.Annals of translational medicine · 2018Article
- Breast size impact on adjuvant radiotherapy adverse effects and dose parameters in treatment planning.Radiology and oncology · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.