Evidence map›Paper›PMID 29616292›Full record

SynthesisPediatric cardiology2018

Racial Variation in Echocardiographic Reference Ranges for Left Chamber Dimensions in Children and Adolescents: A Systematic Review.

Edith D Majonga, Gabrielle Norrish, Andrea M Rehman, Katharina Kranzer, Hilda A Mujuru, Kusum Nathoo, Jon O Odland, Juan P Kaski, Rashida A Ferrand

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Pediatric cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

Edith D MajongaLondon School of Hygiene and Tropical Medicine, London, UK. Edith.Majonga@lshtm.ac.uk.
Gabrielle NorrishCentre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital, London, UK.
Andrea M RehmanLondon School of Hygiene and Tropical Medicine, London, UK.
Katharina KranzerLondon School of Hygiene and Tropical Medicine, London, UK.
Hilda A MujuruDepartment of Pediatrics, University of Zimbabwe, Harare, Zimbabwe.
Kusum NathooDepartment of Pediatrics, University of Zimbabwe, Harare, Zimbabwe.
Jon O OdlandUiT The Arctic University of Norway, Tromsø, Norway.
Juan P KaskiCentre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital, London, UK.
Rashida A FerrandLondon School of Hygiene and Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine · GBGreat Ormond Street Hospital · GBUniversity of Zimbabwe · ZWResearch Center Borstel - Leibniz Lung Center · DEUniversity of Pretoria · ZA

Funding

Medical Research Council MR/K012126/1Wellcome Trust 095878/Z/11/Z
6 · The paper itself

Abstract

Echocardiography plays a critical role in the assessment of cardiac disease. Important differences in echocardiographically derived cardiac chamber dimensions have been previously highlighted in different population groups in adult studies, but this has not been systematically studied in children, whose body size changes throughout childhood. The aim of this study was to review the distribution of available reference ranges for the left cardiac chamber dimensions in older children and adolescents. The following electronic data bases were searched: Medline, Embase and Web of Science were searched to identify studies which have established echocardiographic reference ranges of left heart parameters in children and adolescents from 1975 to December 2017. There was no geographical limitation. All results were imported into Endnote. Retrieved articles were screened and data extracted by two independent reviewers. A total of 4398 studies were retrieved, with 36 studies finally included in this review. 29 (81%) references were from North America and European (Caucasians) populations, with only one study each from Africa and South America. Two-dimensional and M-mode techniques were the most commonly used echocardiography techniques. There were methodological variations in techniques and normalisation of references. Comparison of selected cardiac measures showed significant differences for interventricular septal thickness among Black African, Indian, German and US American children. Available echocardiographic references cannot be generalised to all settings and therefore, there is need for locally relevant reference ranges. Africa and South America are particularly under-represented. Future studies should focus on developing comprehensive echocardiographic reference ranges for children from different racial backgrounds and should use standardised techniques.

Indexed as

Racial GroupsAdolescentBlack PeopleChildEchocardiographyFemaleHeart DiseasesHumansMaleOrgan SizeReference ValuesVentricular SeptumWhite PeopleYoung AdultChildrenEchocardiographyLeft atriumLeft ventricleReference ranges

Identifiers

PMID29616292
PMCPMC5958170
OpenAlexW2795474651

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.