Evidence map›Paper›PMID 29616197›Full record

ArticleFrontiers in cellular and infection microbiology2018

The Use of CRISPR/Cas9 Gene Editing to Confirm Congenic Contaminations in Host-Pathogen Interaction Studies.

Jonathan Ferrand, Nathan P Croft, Geneviève Pépin, Kerrilyn R Diener, Di Wu, Niamh E Mangan, John Pedersen, Mark A Behlke, John D Hayball, Anthony W Purcell and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Jonathan FerrandCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
Nathan P CroftDepartment of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Geneviève PépinCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
Kerrilyn R DienerExperimental Therapeutics Laboratory, School of Pharmacy and Medical Science, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia.
Di WuDepartment of Periodontology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Niamh E ManganCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
John PedersenTissuPath Specialist Pathology, Mount Waverley, VIC, Australia.
Mark A BehlkeIntegrated DNA Technologies Inc., Coralville, IA, United States.
John D HayballExperimental Therapeutics Laboratory, School of Pharmacy and Medical Science, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia.
Anthony W PurcellDepartment of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Richard L FerreroCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
Michael P GantierCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
Monash University · AUHudson Institute of Medical Research · AUIntegrated DNA Technologies (United States) · USTissuPath · AUUniversity of Adelaide · AUUniversity of North Carolina at Chapel Hill · USUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Murine models of

Indexed as

Gene EditingAnimalsAnimals, CongenicCRISPR-Cas SystemsFemaleHost-Pathogen InteractionsHumansMacrophagesMembrane GlycoproteinsMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutSalmonella InfectionsSalmonella typhimuriumToll-Like Receptor 7Membrane GlycoproteinsTlr7 protein, mouseToll-Like Receptor 7background contaminationcongenic miceCRISPR/CAS9host-pathogen interactionsSalmonella

Identifiers

PMID29616197
PMCPMC5867302
OpenAlexW2789938106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.