Evidence map›Paper›PMID 29615983›Full record

ArticleFrontiers in microbiology2018

Spaceflight Modifies

Thomas R Aunins, Keesha E Erickson, Nripesh Prasad, Shawn E Levy, Angela Jones, Shristi Shrestha, Rick Mastracchio, Louis Stodieck, David Klaus, Luis Zea and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
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  11. Review
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  13. Extremophiles in Space Exploration.Indian journal of microbiology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Morphology ofLife (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Thomas R AuninsDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, United States.
Keesha E EricksonDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, United States.
Nripesh PrasadGenomic Services Laboratory, HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States.
Shawn E LevyGenomic Services Laboratory, HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States.
Angela JonesGenomic Services Laboratory, HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States.
Shristi ShresthaGenomic Services Laboratory, HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States.
Rick MastracchioAstronaut Office, Johnson Space Center, National Aeronautics and Space Administration, Washington, DC, United States.
Louis StodieckBioServe Space Technologies, Department of Aerospace Engineering Sciences, University of Colorado Boulder, Boulder, CO, United States.
David KlausDepartment of Aerospace Engineering Sciences, University of Colorado Boulder, Boulder, CO, United States.
Luis ZeaBioServe Space Technologies, Department of Aerospace Engineering Sciences, University of Colorado Boulder, Boulder, CO, United States.
Anushree ChatterjeeDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, United States.
University of Colorado Boulder · USHudsonAlpha Institute for Biotechnology · USNational Aeronautics and Space Administration · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria grown in space experiments under microgravity conditions have been found to undergo unique physiological responses, ranging from modified cell morphology and growth dynamics to a putative increased tolerance to antibiotics. A common theory for this behavior is the loss of gravity-driven convection processes in the orbital environment, resulting in both reduction of extracellular nutrient availability and the accumulation of bacterial byproducts near the cell. To further characterize the responses, this study investigated the transcriptomic response of

Indexed as

antibioticbioastronauticsEscherichia colimicrogravityoxidative stressRNA-sequencingspaceflighttolerance

Identifiers

PMID29615983
PMCPMC5865062
OpenAlexW2790564955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.