ArticleFrontiers in physiology2018
Skeletal Muscle Pyruvate Dehydrogenase Phosphorylation and Lactate Accumulation During Sprint Exercise in Normoxia and Severe Acute Hypoxia: Effects of Antioxidants.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Locally-Sourced Animal Protein Hydrolysates in High-Plant-Protein Diets Can Promote European Seabass Growth and Nutrient Utilization, Reducing Reliance on Fishmeal.Aquaculture nutrition · 2025Article
- Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation.Redox biology · 2023Article
- Angiotensin-Converting Enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle.Scandinavian journal of medicine & science in sports · 2021Article
- RGS5 Determines Neutrophil Migration in the Acute Inflammatory Phase of Bleomycin-Induced Lung Injury.International journal of molecular sciences · 2021Article
- Detailed evaluation of pyruvate dehydrogenase complex inhibition in simulated exercise conditions.Biophysical journal · 2021Article
- Beneficial Effect ofMycobiology · 2020Article
- An integrative approach to the regulation of mitochondrial respiration during exercise: Focus on high-intensity exercise.Redox biology · 2020Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compared to normoxia, during sprint exercise in severe acute hypoxia the glycolytic rate is increased leading to greater lactate accumulation, acidification, and oxidative stress. To determine the role played by pyruvate dehydrogenase (PDH) activation and reactive nitrogen and oxygen species (RNOS) in muscle lactate accumulation, nine volunteers performed a single 30-s sprint (Wingate test) on four occasions: two after the ingestion of placebo and another two following the intake of antioxidants, while breathing either hypoxic gas (P
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Registered trials
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