Evidence map›Paper›PMID 29615857›Full record

ArticleFrontiers in neuroscience2018

Closed-Loop Efficient Searching of Optimal Electrical Stimulation Parameters for Preferential Excitation of Retinal Ganglion Cells.

Tianruo Guo, Chih Yu Yang, David Tsai, Madhuvanthi Muralidharan, Gregg J Suaning, John W Morley, Socrates Dokos, Nigel H Lovell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Context-Dependent Effects of the Ketogenic Diet on Retinal Ganglion Cell Survival and Axonal Regeneration After Optic Nerve Injury.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2023
    Article
  6. Implications of Neural Plasticity in Retinal Prosthesis.Investigative ophthalmology & visual science · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Real-Time Optimization of Retinal Ganglion Cell Spatial Activity in Response to Epiretinal Stimulation.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tianruo GuoGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.
Chih Yu YangGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.
David TsaiGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.
Madhuvanthi MuralidharanGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.
Gregg J SuaningSchool of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, Sydney, NSW, Australia.
John W MorleySchool of Medicine, Western Sydney University, Penrith, NSW, Australia.
Socrates DokosGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.
Nigel H LovellGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability for visual prostheses to preferentially activate functionally-distinct retinal ganglion cells (RGCs) is important for improving visual perception. This study investigates the use of high frequency stimulation (HFS) to elicit RGC activation, using a closed-loop algorithm to search for optimal stimulation parameters for preferential ON and OFF RGC activation, resembling natural physiological neural encoding in response to visual stimuli. We evaluated the performance of a wide range of electrical stimulation amplitudes and frequencies on RGC responses

Indexed as

closed-loop optimizationfrequency and amplitude modulationON and OFF RGCspreferential activationretinal prostheses

Identifiers

PMID29615857
PMCPMC5867314

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.