ArticleScientific reports2018
De novo draft assembly of the Botrylloides leachii genome provides further insight into tunicate evolution.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed.
- Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis: insights into tissue specialization and blastogenesis.Development (Cambridge, England) · 2025Article
- First chromosome-level genome assembly of the colonial chordate model Botryllus schlosseri (Tunicata).GigaScience · 2025Article
- Genetic and functional diversity of allorecognition receptors in the urochordate,bioRxiv : the preprint server for biology · 2024Article
- De novo genome assembly and comparative genomics for the colonial ascidian Botrylloides violaceus.G3 (Bethesda, Md.) · 2023Article
- Physiological changes during torpor favor association withFrontiers in microbiology · 2023Article
- Thyroid-like hormone signaling in invertebrates and its potential role in initial screening of thyroid hormone system disrupting chemicals.Integrated environmental assessment and management · 2023Review
- Using RNA-Seq for Transcriptome Profiling of Botrylloides sp. Regeneration.Methods in molecular biology (Clifton, N.J.) · 2022Article
- The Genome of the "Sea Vomit"Life (Basel, Switzerland) · 2021Article
- The Degenerate Tale of Ascidian Tails.Integrative and comparative biology · 2021Review
- Genome-Wide Identification, Comparison, and Expression Analysis of Transcription Factors in AscidianInternational journal of molecular sciences · 2021Article
- Telomere-to-telomere assembly of the genome of an individual Oikopleura dioica from Okinawa using Nanopore-based sequencing.BMC genomics · 2021Article
- An elongated COI fragment to discriminate botryllid species and as an improved ascidian DNA barcode.Scientific reports · 2021Article
- Stem Cells and Innate Immunity in Aquatic Invertebrates: Bridging Two Seemingly Disparate Disciplines for New Discoveries in Biology.Frontiers in immunology · 2021Review
- Genomic basis of environmental adaptation in the leathery sea squirt (Styela clava).Molecular ecology resources · 2020Article
- Evidence that ABC transporter-mediated autocrine export of an eicosanoid signaling molecule enhances germ cell chemotaxis in the colonial tunicateDevelopment (Cambridge, England) · 2020Article
- Inferring Tunicate Relationships and the Evolution of the Tunicate Hox Cluster with the Genome of Corella inflata.Genome biology and evolution · 2020Article
- ANISEED 2019: 4D exploration of genetic data for an extended range of tunicates.Nucleic acids research · 2020Article
- Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases.Molecular biology and evolution · 2019Article
- Article
- Antero-posterior ectoderm patterning by canonical Wnt signaling during ascidian development.PLoS genetics · 2019Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Tunicates are marine invertebrates that compose the closest phylogenetic group to the vertebrates. These chordates present a particularly diverse range of regenerative abilities and life-history strategies. Consequently, tunicates provide an extraordinary perspective into the emergence and diversity of these traits. Here we describe the genome sequencing, annotation and analysis of the Stolidobranchian Botrylloides leachii. We have produced a high-quality 159 Mb assembly, 82% of the predicted 194 Mb genome. Analysing genome size, gene number, repetitive elements, orthologs clustering and gene ontology terms show that B. leachii has a genomic architecture similar to that of most solitary tunicates, while other recently sequenced colonial ascidians have undergone genome expansion. In addition, ortholog clustering has identified groups of candidate genes for the study of colonialism and whole-body regeneration. By analysing the structure and composition of conserved gene linkages, we observed examples of cluster breaks and gene dispersions, suggesting that several lineage-specific genome rearrangements occurred during tunicate evolution. We also found lineage-specific gene gain and loss within conserved cell-signalling pathways. Such examples of genetic changes within conserved cell-signalling pathways commonly associated with regeneration and development that may underlie some of the diverse regenerative abilities observed in tunicates. Overall, these results provide a novel resource for the study of tunicates and of colonial ascidians.
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