Evidence map›Paper›PMID 29615777›Full record

ArticleScientific reports2018

A comparative analysis of rod bipolar cell transcriptomes identifies novel genes implicated in night vision.

Sasha M Woods, Edward Mountjoy, Duncan Muir, Sarah E Ross, Denize Atan

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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  8. Expression and Localization of Kcne2 in the Vertebrate Retina.Investigative ophthalmology & visual science · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sasha M WoodsBristol Medical School, University of Bristol, Bristol, BS8 1TD, UK. Sasha.Woods@bristol.ac.uk.
Edward MountjoyBristol Medical School, University of Bristol, Bristol, BS8 1TD, UK.ORCID 0000-0002-0626-1821
Duncan MuirBristol Medical School, University of Bristol, Bristol, BS8 1TD, UK.
Sarah E RossDepartments of Neurobiology and Anesthesiology and the Center for Pain Research, University of Pittsburgh, Pittsburgh, 15213-2536, USA.
Denize AtanBristol Medical School, University of Bristol, Bristol, BS8 1TD, UK.
University of Bristol · GBUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the mammalian retina, rods and a specialised rod-driven signalling pathway mediate visual responses under scotopic (dim light) conditions. As rods primarily signal to rod bipolar cells (RBCs) under scoptic conditions, disorders that affect rod or RBC function are often associated with impaired night vision. To identify novel genes expressed by RBCs and, therefore, likely to be involved in night vision, we took advantage of the adult Bhlhe23

Indexed as

Gene Expression ProfilingAnimalsBiomarkers, TumorCarbonic AnhydrasesMiceNerve Tissue ProteinsNight VisionRetinal Bipolar CellsRetinal Rod Photoreceptor CellsBiomarkers, TumorCar8 protein, mouseCarbonic AnhydrasesNerve Tissue Proteins

Identifiers

PMID29615777
PMCPMC5883057
OpenAlexW2795789008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.