Evidence map›Paper›PMID 29615733›Full record

ArticleScientific reports2018

Locus coeruleus complex of the family Delphinidae.

Simona Sacchini, Manuel Arbelo, Cristiano Bombardi, Antonio Fernández, Bruno Cozzi, Yara Bernaldo de Quirós, Pedro Herráez

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Neuromelanin, aging, and neuronal vulnerability in Parkinson's disease.Movement disorders : official journal of the Movement Disorder Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Simona SacchiniVeterinary Histology and Pathology, Institute of Animal Health, University of Las Palmas de Gran Canaria, Veterinary School, Trasmontaña s/n, Arucas, Las Palmas, 35416, Spain. simona.sacchini@ulpgc.es.ORCID 0000-0001-6493-1275
Manuel ArbeloVeterinary Histology and Pathology, Institute of Animal Health, University of Las Palmas de Gran Canaria, Veterinary School, Trasmontaña s/n, Arucas, Las Palmas, 35416, Spain.ORCID 0000-0002-1623-5010
Cristiano BombardiDepartment of Veterinary Medical Science, University of Bologna, Ozzano dell'Emilia, Bologna, 40064, Italy.
Antonio FernándezVeterinary Histology and Pathology, Institute of Animal Health, University of Las Palmas de Gran Canaria, Veterinary School, Trasmontaña s/n, Arucas, Las Palmas, 35416, Spain.
Bruno CozziDepartment of Comparative Biomedicine and Food Science, University of Padova, viale dell'Università 16, Legnaro (PD), 35020, Italy.ORCID 0000-0002-7531-7040
Yara Bernaldo de QuirósVeterinary Histology and Pathology, Institute of Animal Health, University of Las Palmas de Gran Canaria, Veterinary School, Trasmontaña s/n, Arucas, Las Palmas, 35416, Spain.
Pedro HerráezVeterinary Histology and Pathology, Institute of Animal Health, University of Las Palmas de Gran Canaria, Veterinary School, Trasmontaña s/n, Arucas, Las Palmas, 35416, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The locus coeruleus (LC) is the largest catecholaminergic nucleus and extensively projects to widespread areas of the brain and spinal cord. The LC is the largest source of noradrenaline in the brain. To date, the only examined Delphinidae species for the LC has been a bottlenose dolphin (Tursiops truncatus). In our experimental series including different Delphinidae species, the LC was composed of five subdivisions: A6d, A6v, A7, A5, and A4. The examined animals had the A4 subdivision, which had not been previously described in the only Delphinidae in which this nucleus was investigated. Moreover, the neurons had a large amount of neuromelanin in the interior of their perikarya, making this nucleus highly similar to that of humans and non-human primates. This report also presents the first description of neuromelanin in the cetaceans' LC complex, as well as in the cetaceans' brain.

Indexed as

DolphinsAnimalsLocus CoeruleusMelaninsNeuronsTyrosine 3-MonooxygenaseMelaninsneuromelaninTyrosine 3-Monooxygenase

Identifiers

PMID29615733
PMCPMC5883054

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.