ArticleScientific reports2018
Age is reflected in the Fractal Dimensionality of MRI Diffusion Based Tractography.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Complexity in disguise: a systematic review of fractal analysis in psychiatric neuroimaging.European radiology · 2026Pooled it
- Spike dynamics in primate lateral prefrontal cortex during working memory and decision-making: A fractal analysis.iScience · 2026Article
- Plug-and-Play Self-Supervised Denoising for Pulmonary Perfusion MRI.Bioengineering (Basel, Switzerland) · 2025Article
- Ventricular volume adjustment of brain regions depicts brain changes associated with HIV infection and aging better than intracranial volume adjustment.Frontiers in neurology · 2025Article
- Fractal Time Series: Background, Estimation Methods, and Performances.Advances in neurobiology · 2024Review
- Fractal Dimension Analysis in Neurological Disorders: An Overview.Advances in neurobiology · 2024Review
- Hippocampal and Medial Prefrontal Cortex Fractal Spiking Patterns Encode Episodes and Rules.Chaos, solitons, and fractals · 2023Article
- The fractal brain: scale-invariance in structure and dynamics.Cerebral cortex (New York, N.Y. : 1991) · 2023Review
- A correlational study between microstructural, macrostructural and functional age-related changes in the human visual cortex.PloS one · 2023Article
- Reduced cortical complexity in patients with thyroid-associated ophthalmopathy.Brain imaging and behavior · 2022Article
- Sexual dimorphism in the relationship between brain complexity, volume and general intelligence (g): a cross-cohort study.Scientific reports · 2022Article
- Fractal structures arising from interfacial instabilities in bio-oil atomization.Scientific reports · 2021Article
- Interactions Between Aging and Alzheimer's Disease on Structural Brain Networks.Frontiers in aging neuroscience · 2021Article
- Toward a more reliable characterization of fractal properties of the cerebral cortex of healthy subjects during the lifespan.Scientific reports · 2020Article
- Reduced Cortical Complexity in Cirrhotic Patients with Minimal Hepatic Encephalopathy.Neural plasticity · 2020Article
- Evaluation of the 3D fractal dimension as a marker of structural brain complexity in multiple-acquisition MRI.Human brain mapping · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fractal analysis is a widely used tool to analyze the geometrical complexity of biological structures. The geometry of natural objects such as plants, clouds, cellular structures, blood vessel, and many others cannot be described sufficiently with Euclidian geometric properties, but can be represented by a parameter called the fractal dimension. Here we show that a specific estimate of fractal dimension, the correlation dimension, is able to describe changes in the structural complexity of the human brain, based on data from magnetic resonance diffusion imaging. White matter nerve fiber bundles, represented by tractograms, were analyzed with regards to geometrical complexity, using fractal geometry. The well-known age-related change of white matter tissue was used to verify changes by means of fractal dimension. Structural changes in the brain were successfully be observed and quantified by fractal dimension and compared with changes in fractional anisotropy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.