Evidence map›Paper›PMID 29615595›Full record

ArticleJournal of developmental biology2016

Asxl2

Rachel Brunner, Hsiao-Lei Lai, Zane Deliu, Elan Melman, David L Geenen, Q Tian Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of developmental biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Relationship betweenJournal of thoracic disease · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rachel BrunnerDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA. rbrunn2@uic.edu.
Hsiao-Lei LaiDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA. hsiaoleilai@gmail.com.ORCID 0000-0001-6494-6055
Zane DeliuDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA. zdeliu2@uic.edu.
Elan MelmanDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA. emelma2@illinois.edu.
David L GeenenDepartment of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL 60612, USA. geenend@gvsu.edu.
Q Tian WangDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA. quntianw@live.com.
University of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart attacks affect more than seven million people worldwide each year. A heart attack, or myocardial infarction, may result in the death of a billion cardiomyocytes within hours. The adult mammalian heart does not have an effective mechanism to replace lost cardiomyocytes. Instead, lost muscle is replaced with scar tissue, which decreases blood pumping ability and leads to heart failure over time. Here, we report that the loss of the chromatin factor ASXL2 results in spontaneous proliferation and cardiogenic differentiation of a subset of interstitial non-cardiomyocytes. The adult

Indexed as

cardiogeniccardiomyocytechromatin factorepigeneticheartproliferationregeneration

Identifiers

PMID29615595
PMCPMC5831801
OpenAlexW2548739891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.