Evidence map›Paper›PMID 29615551›Full record

ReviewJournal of developmental biology2018

The Biology of SUMO-Targeted Ubiquitin Ligases in Drosophila Development, Immunity, and Cancer.

Mona Abed, Eliya Bitman-Lotan, Amir Orian

Open access · goldAbstract readReview
In one paragraph

Review in Journal of developmental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. The role of SUMOylation during development.Biochemical Society transactions · 2020
    Review
  8. SUMOylation in development and neurodegeneration.Development (Cambridge, England) · 2020
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mona AbedGenentech, 1 DNA Way, South San Francisco, CA 94080, USA. abed.monah@gene.com.
Eliya Bitman-LotanRappaport Research Institute and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3109610, Israel. eliyabit@technion.ac.il.
Amir OrianRappaport Research Institute and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3109610, Israel. mdoryan@tx.technion.ac.il.
Rappaport Family Institute for Research in the Medical Sciences · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ubiquitin and SUMO (small ubiquitin-like modifier) pathways modify proteins that in turn regulate diverse cellular processes, embryonic development, and adult tissue physiology. These pathways were originally discovered biochemically in vitro, leading to a long-standing challenge of elucidating both the molecular cross-talk between these pathways and their biological importance. Recent discoveries in

Indexed as

cancerdevelopmentDgrngene regulationimmunitySUMOSUMO-targeted ubiquitin ligases RNF4transcriptionubiquitin

Identifiers

PMID29615551
PMCPMC5875560
OpenAlexW2782375087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.