Evidence map›Paper›PMID 29615509›Full record

ArticlemBio2018

MYR1-Dependent Effectors Are the Major Drivers of a Host Cell's Early Response to

Adit Naor, Michael W Panas, Nicole Marino, Michael J Coffey, Christopher J Tonkin, John C Boothroyd

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 61 citations in OpenAlex.

  1. A Suite of EightbioRxiv : the preprint server for biology · 2026
    Article
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  4. Article
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  6. Article
  7. A Combination of Four Nuclear Targeted Effectors ProtectsbioRxiv : the preprint server for biology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Annual review of microbiology · 2020
    Review
  17. Article
  18. mSphere · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Adit Naor *Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-4770-3099
Michael W Panas *Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Nicole MarinoDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Michael J CoffeyDivision of Infection and Immunity, The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.
Christopher J TonkinDivision of Infection and Immunity, The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.ORCID 0000-0002-7036-6222
John C BoothroydDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA jboothr@stanford.edu.
Stanford University · USThe University of Melbourne · AU

Funding

Toxoplasma Rhoptry FunctionR01AI021423 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 1985 to 2018
$7.8M
Identifying The Machinery That Translocates Toxoplasma Effectors Into The Host CellR01AI129529 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 2018 to 2021
$2.2M
ANTIGENS OF TOXOPLASMA GONDII AND THEIR GENESR37AI021423 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 1994 to 2003
$1.6M
Role of c-Myc up-regulation in Toxoplasma infectionR21AI112962 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 2015 to 2016
$435k
The role of Toxoplasma gondii amino acid hydroxylase 2 in chronic infectionF31AI120649 · NIAID · STANFORD UNIVERSITY · PI MARINO, NICOLE D. · 2015 to 2016
$70k
NIAID NIH HHS F31 AI120649NIAID NIH HHS R01 AI021423NIAID NIH HHS R01 AI129529NIAID NIH HHS R21 AI112962NIAID NIH HHS R37 AI021423
6 · The paper itself

Abstract

The obligate intracellular parasite

Indexed as

Host-Pathogen InteractionsCells, CulturedFibroblastsGene DeletionGene Expression ProfilingHumansMembrane Transport ProteinsProtein TransportSequence Analysis, RNAToxoplasmaToxoplasmosisVirulence FactorsMembrane Transport ProteinsVirulence Factorseffector functionshost-parasite relationshiphost responseToxoplasma gondii

Identifiers

PMID29615509
PMCPMC5885026
OpenAlexW2796090844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.