Evidence map›Paper›PMID 29615497›Full record

ArticlemBio2018

Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection.

Elizabeth Diago-Navarro, Michael P Motley, Gonzalo Ruiz-Peréz, Winnie Yu, Julianne Austin, Bruna M S Seco, Guozhi Xiao, Aniska Chikhalya, Peter H Seeberger, Bettina C Fries

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Monoclonal Antibodies Targeting Bacterial Infections: A Broad Review of the Field.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  3. Article
  4. Article
  5. Materials today. Bio · 2026
    Article
  6. Carbapenem-resistant hypervirulentFrontiers in microbiology · 2026
    Review
  7. Article
  8. Article
  9. O-antigen polysaccharides inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. A Comprehensive Overview ofInfection and drug resistance · 2025
    Review
  15. Article
  16. Virulence · 2024
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Elizabeth Diago-NavarroDepartment of Medicine, Infectious Disease Division, Stony Brook University, Stony Brook, New York, USA.
Michael P MotleyDepartment of Medicine, Infectious Disease Division, Stony Brook University, Stony Brook, New York, USA.
Gonzalo Ruiz-PerézUniversidad Francisco de Vitoria, Pozuelo de Alarcón, Madrid, Spain.
Winnie YuDepartment of Medicine, Infectious Disease Division, Stony Brook University, Stony Brook, New York, USA.
Julianne AustinDepartment of Medicine, Infectious Disease Division, Stony Brook University, Stony Brook, New York, USA.
Bruna M S SecoDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany.
Guozhi XiaoDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany.
Aniska ChikhalyaDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.
Peter H SeebergerDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany.
Bettina C FriesDepartment of Medicine, Infectious Disease Division, Stony Brook University, Stony Brook, New York, USA Bettina.fries@stonybrookmedicine.edu.
Stony Brook University · USMax Planck Institute of Colloids and Interfaces · DEUniversidad Francisco de Vitoria · ES

Funding

Development of antibodies to capsule of carbapenem resistant Klebsiella pneumoniaR21AI114259 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI FRIES, BETTINA · 2015 to 2016
$435k
Studying the role of anti-capsular antibodies in mediating pathogenesis of carbapenem-resistant Klebsiella pneumoniaeF30AI140611 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI MOTLEY, MICHAEL PETER · 2019 to 2021
$128k
BLRD VA I01 BX003741NIAID NIH HHS F30 AI140611NIAID NIH HHS R21 AI114259
6 · The paper itself

Abstract

Carbapenem-resistant (CR) sequence type 258 (ST258)

Indexed as

Agglutination TestsAnimalsAnimal StructuresAntibodies, BacterialAntibodies, MonoclonalCarbapenem-Resistant EnterobacteriaceaeCells, CulturedDisease Models, AnimalImmunoglobulin GKlebsiella InfectionsKlebsiella pneumoniaeMacrophagesMiceNeutrophilsPhagocytosisPolysaccharides, BacterialAntibodies, BacterialAntibodies, MonoclonalImmunoglobulin GPolysaccharides, Bacterialadjuvant therapyantibiotic resistancecarbapenem resistanceinfection protectionKlebsiella pneumoniaemonoclonal antibodies

Identifiers

PMID29615497
PMCPMC5885035
OpenAlexW2795694182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.