ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
Alpha Oscillations Are Causally Linked to Inhibitory Abilities in Ageing.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A Systematic Review of tACS Effects on Cognitive Functioning in Older Adults Across the Healthy to Dementia Spectrum.Neuropsychology review · 2024Pooled it
- Efficacy of Transcranial Alternating Current Stimulation in the Enhancement of Working Memory Performance in Healthy Adults: A Systematic Meta-Analysis.Neuromodulation : journal of the International Neuromodulation Society · 2023Pooled it
- A Systematic Review of Non-invasive Brain Stimulation Applications to Memory in Healthy Aging.Frontiers in neurology · 2020Pooled it
- The effects of transcranial alternating current stimulation (tACS) at individual alpha peak frequency (iAPF) on motor cortex excitability in young and elderly adults.Experimental brain research · 2018Trial
- Supporting Visual Working Memory in Healthy Aging: A Review of Current Interventions and Perspectives on Future Approaches.Brain sciences · 2026Review
- Closed-loop transcranial alternating current stimulation (tACS) reduces cue reactivity and improves inhibitory control in methamphetamine use disorder with frequency and timing specificity.Molecular psychiatry · 2026Article
- Review
- Prolonged Visual Entrainment Induces Long-Lasting Alpha-Band Modulations.Psychophysiology · 2026Article
- Backward alpha band oscillations shape perceptual bias under probabilistic cues.Communications biology · 2026Article
- Parietal alpha frequency shapes own-body perception by modulating the temporal integration of bodily signals.Nature communications · 2026Article
- Coupling between neural oscillations and white matter integrity reveals cognitive computational profiles following COVID-19.Scientific reports · 2025Article
- Amplitude of Intracranial Induced Electric Fields Does Not Linearly Decrease with Age: A Computational Study of Anatomical Effects in Adults.Biosensors · 2025Article
- Neural Mechanisms Underlying Robust Target Selection in Response to Microstimulation of the Oculomotor System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- The effects of amplitude modulated transcranial alternating current stimulation on working memory of college students.Frontiers in human neuroscience · 2025Article
- Broadscale dampening of uncertainty adjustment in the aging brain.Nature communications · 2024Article
- Sensory stimulation enhances visual working memory capacity.Communications psychology · 2024Article
- Association between electroencephalogram alpha-band oscillations and executive and processing functions in patients with cerebral small vessel diseases.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Theta-gamma-coupling as predictor of working memory performance in young and elderly healthy people.Molecular brain · 2024Article
- Improving working memory by electrical stimulation and cross-frequency coupling.Molecular brain · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging adults typically show reduced ability to ignore task-irrelevant information, an essential skill for optimal performance in many cognitive operations, including those requiring working memory (WM) resources. In a first experiment, young and elderly human participants of both genders performed an established WM paradigm probing inhibitory abilities by means of valid, invalid, and neutral retro-cues. Elderly participants showed an overall cost, especially in performing invalid trials, whereas younger participants' general performance was comparatively higher, as expected.Inhibitory abilities have been linked to alpha brain oscillations but it is yet unknown whether in aging these oscillations (also typically impoverished) and inhibitory abilities are causally linked. To probe this possible causal link in aging, we compared in a second experiment parietal alpha-transcranial alternating current stimulation (tACS) with either no stimulation (Sham) or with two control stimulation frequencies (theta- and gamma-tACS) in the elderly group while performing the same WM paradigm. Alpha- (but not theta- or gamma-) tACS selectively and significantly improved performance (now comparable to younger adults' performance in the first experiment), particularly for invalid cues where initially elderly showed the highest costs. Alpha oscillations are therefore causally linked to inhibitory abilities and frequency-tuned alpha-tACS interventions can selectively change these abilities in the elderly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.