Evidence map›Paper›PMID 29615143›Full record

Observational studyPublic health nutrition2018

Recovery and relapse from severe acute malnutrition after treatment: a prospective, observational cohort trial in Pakistan.

Nancy M Dale, Laila Salim, Lindsey Lenters, Salim Sadruddin, Mark Myatt, Stanley H Zlotkin

Abstract readObservational Study
In one paragraph

Observational study in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nancy M Dale1Tampere Centre for Child Health Research,University of Tampere and Tampere University Hospital,Tampere,Finland.
Laila Salim3Save the Children Canada,Toronto,Canada.
Lindsey Lenters4Public Health Ontario,Toronto,Canada.
Salim Sadruddin5Global Malaria Programme,World Health Organization,Geneva,Switzerland.
Mark Myatt6Brixton Health,Llawryglyn,UK.
Stanley H Zlotkin2Centre for Global Child Health,Hospital for Sick Children,525 University Avenue,Suite 701,Toronto,Ontario,Canada,M5G 2L3.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveMillions of children suffer from severe acute malnutrition (SAM) in low- and middle- income countries. Much is known about the effectiveness of community treatment programmes (CMAM) but little is known about post-discharge outcomes after successful treatment. The present study aimed to evaluate post-discharge outcomes of children cured of SAM.

designProspective, observational cohort study. Children with SAM who were discharged as cured were followed monthly for 6 months or until they experienced relapse to SAM. 'Cure' was defined as a child achieving a mid-upper arm circumference (MUAC) of ≥115 mm with ≥15 % weight gain after loss of oedema. Relapse was defined as a child with MUAC<115 mm and/or oedema at any monthly visit.

settingSave the Children CMAM programme in Swabi, Pakistan, from January 2012 to December 2014. SUBJECTS: Children aged 6-59 months (n 117) discharged as cured from the CMAM programme were eligible for the study and followed for 6 months.

resultsOne hundred children (92·6 %) remained free of SAM, eight (7·4 %) relapsed to SAM, nine (8·3 %) were lost to follow-up and none died. Most relapses occurred within 3 months of discharge (mean time to relapse 73·4 (sd 36·2) d). At enrolment, 90 % had moderate acute malnutrition (MAM) and 10 % were not malnourished. By the end of 6 months, 35 % persisted with MAM and the remaining were not malnourished.

conclusionsIn rural Pakistan, fewer than 10 % of children cured of SAM relapsed. The first 3 months is the most vulnerable time.

Indexed as

Child, PreschoolFemaleHumansInfantMalePakistanProspective StudiesRecurrenceSevere Acute MalnutritionTreatment OutcomeChildrenCommunity management of acute malnutritionMalnutritionRecoveryRelapseSevere acute malnutrition

Identifiers

PMID29615143
PMCPMC11106019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.