Evidence map›Paper›PMID 29615129›Full record

ArticleBMC research notes2018

Antimicrobial susceptibility pattern of Staphylococcus aureus isolates from clinical specimens at Kenyatta National Hospital.

Wilfred Gitau, Moses Masika, Moses Musyoki, Beatrice Museve, Titus Mutwiri

Abstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Global prevalence of macrolide-resistantFrontiers in microbiology · 2025
    Pooled it
  2. Phenotypic and Genotypic Analyses of Antimicrobial Resistance Patterns ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
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  15. Characteristics ofPathogens (Basel, Switzerland) · 2022
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  20. Healthcare-associated Infections in Pediatric Patients in Neurotrauma Intensive Care Unit: A Retrospective Analysis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wilfred GitauDepartment of Medical Microbiology, University of Nairobi, P.O Box 19676-00202, Nairobi, Kenya. gwilfredrz@gmail.com.
Moses MasikaDepartment of Medical Microbiology, University of Nairobi, P.O Box 19676-00202, Nairobi, Kenya.
Moses MusyokiDepartment of Medical Microbiology, University of Nairobi, P.O Box 19676-00202, Nairobi, Kenya.
Beatrice MuseveDepartment of Laboratory Medicine, Microbiology, Kenyatta National Hospital, P.O Box 20723-00202, Nairobi, Kenya.
Titus MutwiriDepartment of Medical Laboratory, Kenya Methodist University, P.O Box 45240-00100, Nairobi, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine antibiotic susceptibility pattern of S. aureus isolates from clinical specimens collected from patients at Kenyatta National Hospital from March 2014-February 2016, and to determine the prevalence and quarterly trends of MRSA throughout the study period.

resultsA total of 944 S. aureus isolates were analyzed. High sensitivity of S. aureus was observed for quinupristin/dalfopristin (100%), tigecycline (98.2), imipenem (98%), nitrofurantoin (97.6%), linezolid (97.3%), teicoplanin (97.1%) and vancomycin (95.1%). High resistance was recorded against penicillin G (91.9%), trimethoprim/sulfamethoxazole (56.9%) and tetracycline (33.2%). MRSA prevalence among the patients at KNH was 27.8%. Highest proportion (80%) of MRSA was in burns unit. Both MRSA and MSSA were highly susceptible to quinupristin/dalfopristin, tigecycline, linezolid, nitrofurantoin, ampicillin/sulbactam and vancomycin and showed high resistance to commonly used antibiotics such as gentamycin, erythromycin, levofloxacin and tetracycline. A majority of isolates were from pus specimen (68%).

Indexed as

Anti-Bacterial AgentsCross InfectionDrug Resistance, BacterialHospitalsHumansKenyaMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsRetrospective StudiesStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsDrug resistanceKenyatta National HospitalMethicillin resistant Staphylococcus aureusStaphylococcus aureusSusceptibilityVancomycin

Identifiers

PMID29615129
PMCPMC5883409

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.