ArticleBMC developmental biology2018
The skeletal ontogeny of Astatotilapia burtoni - a direct-developing model system for the evolution and development of the teleost body plan.
Article in BMC developmental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Actinotrichia-independent developmental mechanisms of spiny rays facilitate the morphological diversification of Acanthomorpha fish fins.Nature communications · 2026Article
- Combined mutations of hoxa13a, hoxa13b, and hoxd13a lead to structural shifts in zebrafish soft fin rays providing insight into spiny ray evolution.PLoS genetics · 2026Article
- Dorsoventral limb patterning in paired appendages emerged via regulatory repurposing of an ancestral posterior fin module.Molecular biology and evolution · 2026Article
- The Early Development of the Blue-Eye Cichlid, Cryptoheros spilurus (Cichliformes: Cichlidae).Evolution & development · 2025Article
- From hatching to juvenile: Larval development of Vieja fenestrata (Teleostei: Cichlidae).Journal of fish biology · 2024Article
- Anterior-posterior constraint on Hedgehog signaling by hhip in teleost fin elaboration.Development (Cambridge, England) · 2024Article
- Genetic and Developmental Divergence in the Neural Crest Program between Cichlid Fish Species.Molecular biology and evolution · 2024Article
- A whole-body micro-CT scan library that captures the skeletal diversity of Lake Malawi cichlid fishes.Scientific data · 2024Article
- Meristic co-evolution and genomic co-localization of lateral line scales and vertebrae in Central American cichlid fishes.Ecology and evolution · 2024Article
- The dwarf neon rainbowfish Melanotaenia praecox, a small spiny-rayed fish with potential as a new Acanthomorpha model fish: I. Fin ray ontogeny and postembryonic staging.Developmental dynamics : an official publication of the American Association of Anatomists · 2024Article
- Genetic and developmental divergence in the neural crest programme between cichlid fish species.bioRxiv : the preprint server for biology · 2024Article
- Morphological and temporal variation in early embryogenesis contributes to species divergence in Malawi cichlid fishes.Evolution & development · 2023Article
- East African cichlid fishes.EvoDevo · 2023Review
- Morphological evolution and diversity of pectoral fin skeletons in teleosts.Zoological letters · 2022Article
- Morphological characters in light of new molecular phylogenies: the caudal-fin skeleton of Ovalentaria.Royal Society open science · 2022Article
- Spiny and soft-rayed fin domains in acanthomorph fish are established through a BMP-Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Development of the caudal-fin skeleton reveals multiple convergent fusions within Atherinomorpha.Frontiers in zoology · 2021Article
- Exploring the Expression of Cardiac Regulators in a Vertebrate Extremophile: The Cichlid FishJournal of developmental biology · 2020Article
- Sarcopterygian fin ontogeny elucidates the origin of hands with digits.Science advances · 2020Article
- Neural innervation as a potential trigger of morphological color change and sexual dimorphism in cichlid fish.Scientific reports · 2020Article
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5 authors.
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Abstract
backgroundThe experimental approach to the evolution and development of the vertebrate skeleton has to a large extent relied on "direct-developing" amniote model organisms, such as the mouse and the chicken. These organisms can however only be partially informative where it concerns secondarily lost features or anatomical novelties not present in their lineages. The widely used anamniotes Xenopus and zebrafish are "indirect-developing" organisms that proceed through an extended time as free-living larvae, before adopting many aspects of their adult morphology, complicating experiments at these stages, and increasing the risk for lethal pleiotropic effects using genetic strategies.
resultsHere, we provide a detailed description of the development of the osteology of the African mouthbrooding cichlid Astatotilapia burtoni, primarily focusing on the trunk (spinal column, ribs and epicentrals) and the appendicular skeleton (pectoral, pelvic, dorsal, anal, caudal fins and scales), and to a lesser extent on the cranium. We show that this species has an extremely "direct" mode of development, attains an adult body plan within 2 weeks after fertilization while living off its yolk supply only, and does not pass through a prolonged larval period.
conclusionsAs husbandry of this species is easy, generation time is short, and the species is amenable to genetic targeting strategies through microinjection, we suggest that the use of this direct-developing cichlid will provide a valuable model system for the study of the vertebrate body plan, particularly where it concerns the evolution and development of fish or teleost specific traits. Based on our results we comment on the development of the homocercal caudal fin, on shared ontogenetic patterns between pectoral and pelvic girdles, and on the evolution of fin spines as novelty in acanthomorph fishes. We discuss the differences between "direct" and "indirect" developing actinopterygians using a comparison between zebrafish and A. burtoni development.
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