Evidence map›Paper›PMID 29614789›Full record

ArticleCancers2018

EBV⁺ and MSI Gastric Cancers Harbor High PD-L1/PD-1 Expression and High CD8⁺ Intratumoral Lymphocytes.

Simona De Rosa, Nora Sahnane, Maria Grazia Tibiletti, Francesca Magnoli, Alessandro Vanoli, Fausto Sessa, Anna Maria Chiaravalli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. The density of tumour infiltrating lymphocytes in oesophago-gastric cancer varies with disease stage, geographical region and treatment: a post hoc analysis of nine phase III clinical trials.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Simona De RosaDepartment of Pathology, Ospedale di Circolo, 21100 Varese, Italy. simona-derosa@hotmail.com.
Nora SahnaneDepartment of Surgical and Medical Sciences, University of Insubria, 21100 Varese, Italy. n.sahnane@gmail.com.ORCID 0000-0002-6227-8628
Maria Grazia TibilettiDepartment of Pathology, Ospedale di Circolo, 21100 Varese, Italy. mariagrazia.tibiletti@asst-settelaghi.it.
Francesca MagnoliDepartment of Pathology, Ospedale di Circolo, 21100 Varese, Italy. francesca.magnoli@asst-settelaghi.it.
Alessandro VanoliDepartment of Molecular Medicine, University of Pavia and IRCCS S. Matteo Hospital, Pavia 27100, Italy. alessandro.vanoli@unipv.it.
Fausto SessaDepartment of Pathology, Ospedale di Circolo, 21100 Varese, Italy. fausto.sessa@uninsubria.it.
Anna Maria ChiaravalliDepartment of Pathology, Ospedale di Circolo, 21100 Varese, Italy. annamaria.chiaravalli@asst-settelaghi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both EBV⁺ and MSI gastric cancers (GCs) have high lymphoid infiltration which is rare in MSS/EBV

Indexed as

EBVgastric cancerMSIPD-L1tumor infiltrating lymphocytes

Identifiers

PMID29614789
PMCPMC5923357

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.