Evidence map›Paper›PMID 29614714›Full record

ArticleMarine drugs2018

Cloning, Synthesis and Functional Characterization of a Novel α-Conotoxin Lt1.3.

Jinqin Chen, Li Liang, Huying Ning, Fengtao Cai, Zhuguo Liu, Longxiao Zhang, Liangyi Zhou, Qiuyun Dai

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. GABAMedComm · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jinqin ChenBeijing Institute of Biotechnology, Beijing 100071, China. chenjq0210@163.com.
Li LiangBeijing Institute of Biotechnology, Beijing 100071, China. ranran21501@163.com.
Huying NingBeijing Institute of Biotechnology, Beijing 100071, China. tmu_ninghy@163.com.
Fengtao CaiBeijing Institute of Biotechnology, Beijing 100071, China. fengtaoc@126.com.
Zhuguo LiuBeijing Institute of Biotechnology, Beijing 100071, China. liuzhuguo@126.com.
Longxiao ZhangBeijing Institute of Biotechnology, Beijing 100071, China. chonglai1988@163.com.
Liangyi ZhouBeijing Institute of Biotechnology, Beijing 100071, China. m13517221660@163.com.
Qiuyun DaiBeijing Institute of Biotechnology, Beijing 100071, China. qy_dai@yahoo.com.ORCID 0000-0003-2062-8332
Anhui University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Conotoxins (α-CTxs) are small peptides composed of 11 to 20 amino acid residues with two disulfide bridges. Most of them potently and selectively target nicotinic acetylcholine receptor (nAChR) subtypes, and a few were found to inhibit the GABA

Indexed as

Amino Acid MotifsAmino Acid SequenceAnimalsCalcium Channel BlockersCalcium Channels, N-TypeConotoxinsConus SnailHEK293 CellsHumansInhibitory Concentration 50Nicotinic AntagonistsOceans and SeasOocytesPatch-Clamp TechniquesReceptors, NicotinicStructure-Activity RelationshipCalcium Channel BlockersCalcium Channels, N-TypeConotoxinsNicotinic AntagonistsReceptors, NicotiniccloningGABABR-coupled Cav2.2Lt1.3synthesisα3β2 nAChRsα-conotoxins

Identifiers

PMID29614714
PMCPMC5923399
OpenAlexW2794547780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.