ArticleJournal of Alzheimer's disease : JAD2018
Gait in Mild Alzheimer's Disease: Feasibility of Multi-Center Measurement in the Clinic and Home with Body-Worn Sensors: A Pilot Study.
Article in Journal of Alzheimer's disease : JAD, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Aesthetic Experience in the Acceptance of Wearable Technology for People With Dementia: Critical Interpretive Synthesis.JMIR aging · 2025Pooled it
- Continuous Movement Monitoring at Home Through Wearable Devices: A Systematic Review.Sensors (Basel, Switzerland) · 2025Pooled it
- Enhancing Enrollment and Adherence in Long-Term Wearable Research on Dementia: Qualitative Systematic Review and Meta-Synthesis.JMIR aging · 2025Pooled it
- Using Digital Technology to Quantify Habitual Physical Activity in Community Dwellers With Cognitive Impairment: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Trial
- Real-world data capture of daily limb loading using force-sensing insoles: Feasibility and lessons learned.Journal of biomechanics · 2024Trial
- Laboratory-based turning performance during walking in people with mild cognitive impairment and dementia.Journal of Alzheimer's disease : JAD · 2026Article
- Wearable Sensor Technologies and Gait Analysis for Early Detection of Dementia: Trends and Future Directions.Sensors (Basel, Switzerland) · 2025Review
- Capture of Longitudinal Change in Real-Life Walking in Cerebellar Ataxia Increases Patient Relevance and Effect Size.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Sensor-based motion analysis for dementia detection: a systematic review.Frontiers in digital health · 2025Review
- Gait Characteristics and Neuroanatomical Alterations in Obstructive Sleep Apnea-Hypopnea Syndrome.Nature and science of sleep · 2025Article
- DUI Detection From Gait Using a Multichannel 1DCNN-Attention-BiLSTM Framework.IEEE access : practical innovations, open solutions · 2025Article
- Exploring the Effect of Sampling Frequency on Real-World Mobility, Sedentary Behaviour, Physical Activity and Sleep Outcomes Measured with Wearable Devices in Rheumatoid Arthritis: Feasibility, Usability and Practical Considerations.Bioengineering (Basel, Switzerland) · 2024Article
- Behavioral Alterations of Spatial Cognition and Role of the Apolipoprotein E-ε4 in Patients with MCI Due to Alzheimer's Disease: Results from the BDSC-MCI Project.Journal of clinical medicine · 2024Article
- Quantitative Gait and Balance Outcomes for Ataxia Trials: Consensus Recommendations by the Ataxia Global Initiative Working Group on Digital-Motor Biomarkers.Cerebellum (London, England) · 2024Review
- Reliability of Wearable Sensors for Assessing Gait and Chair Stand Function at Home in People With Knee Osteoarthritis.Arthritis care & research · 2023Article
- IoT-Enabled Gait Assessment: The Next Step for Habitual Monitoring.Sensors (Basel, Switzerland) · 2023Review
- Spatial orientation, postural control and the vestibular system in healthy elderly and Alzheimer's dementia.PeerJ · 2023Review
- Associations Between Local Area Deprivation and Physical Activity Participation in People with Cognitive Impairment in the North East of England.Journal of Alzheimer's disease : JAD · 2023Article
- Capturing Measures That Matter: The Potential Value of Digital Measures of Physical Behavior for Alzheimer's Disease Drug Development.Journal of Alzheimer's disease : JAD · 2023Review
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
17 authors at 5 institutions in 2 countries.
Funding
Abstract
Gait is emerging as a potential diagnostic tool for cognitive decline. The 'Deep and Frequent Phenotyping for Experimental Medicine in Dementia Study' (D&FP) is a multicenter feasibility study embedded in the United Kingdom Dementia Platform designed to determine participant acceptability and feasibility of extensive and repeated phenotyping to determine the optimal combination of biomarkers to detect disease progression and identify early risk of Alzheimer's disease (AD). Gait is included as a clinical biomarker. The tools to quantify gait in the clinic and home, and suitability for multi-center application have not been examined. Six centers from the National Institute for Health Research Translational Research Collaboration in Dementia initiative recruited 20 individuals with early onset AD. Participants wore a single wearable (tri-axial accelerometer) and completed both clinic-based and free-living gait assessment. A series of macro (behavioral) and micro (spatiotemporal) characteristics were derived from the resultant data using previously validated algorithms. Results indicate good participant acceptability, and potential for use of body-worn sensors in both the clinic and the home. Recommendations for future studies have been provided. Gait has been demonstrated to be a feasible and suitable measure, and future research should examine its suitability as a biomarker in AD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.